Results 91 to 100 of about 4,427 (164)

Stabilization of the catalytically active structure of a molybdenum‐dependent formate dehydrogenase depends on a highly conserved lysine residue

open access: yesThe FEBS Journal, EarlyView.
Molybdenum‐dependent formate dehydrogenases (Mo‐FDHs) contain a strictly conserved lysine residue (K44) in the vicinity of an electron‐transferring [4Fe‐4S] cluster and a catalytically active molybdenum atom coordinated by two molybdopterins (MPT‐1 and MPT‐2).
Feilong Li, Michael Lienemann
wiley   +1 more source

Cuts, Cats, and Complete Graphs [PDF]

open access: yesarXiv
We introduce the game of Cat Herding, where an omnipresent herder slowly cuts down a graph until an evasive cat player has nowhere to go. The number of cuts made is the score of a game, and we study the score under optimal play. In this paper, we begin by deriving some general results, and then we determine the precise cat number for paths, cycles ...
arxiv  

Free construction of CAT(1) spaces [PDF]

open access: yesarXiv, 2005
We construct several non-trivial examples of CAT(1) spaces by using the idea of free construction.
arxiv  

Far‐right movement parties in Europe: Two perspectives

open access: yesNations and Nationalism, EarlyView.
Abstract Taking as a starting point the growing body of scholarship on movement parties of the far right, this research note undertakes a reflection on the boundaries of the movement party concept from two distinct angles – the established interactive‐mobilisational approach and the more recent discursive‐organisational one – and their empirical ...
Seongcheol Kim
wiley   +1 more source

To be, or not to be cleaved: Directed evolution of a canonical serine protease inhibitor against active and inactive protease pair identifies binding loop residue critical for prevention of proteolytic cleavage

open access: yesProtein Science, Volume 34, Issue 5, May 2025.
Abstract Canonical serine protease inhibitor proteins occupy the substrate‐binding groove of their target enzyme via a surface loop. Unlike true substrates, inhibitors are cleaved by the target protease extremely slowly. Here, we applied an unbiased directed evolution approach to investigate which loop residues hamper proteolytic cleavage while ...
Zsombor Köller   +8 more
wiley   +1 more source

Characterization and Inhibition of the Chaperone Function of Plasmodium falciparum Glucose‐Regulated Protein 94 kDa (Pf Grp94)

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 93, Issue 5, Page 957-971, May 2025.
ABSTRACT Plasmodium falciparum expresses four heat shock protein 90 (Hsp90) members. Among these, one, glucose‐regulated protein 94 (PfGrp94), is localized in the endoplasmic reticulum (ER). Both the cytosolic and ER‐based Hsp90s are essential for parasite survival under all growth conditions.
Florence Lisa Muzenda   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy