Results 141 to 150 of about 5,161 (208)

Amino Acid Substitutions in Loop C of Arabidopsis PIP2 Aquaporins Alters the Permeability of CO2

Plant, Cell &Environment, EarlyView.
ABSTRACT The transport of CO2 across biomembranes in plant cells is essential for efficient photosynthesis. Some aquaporins capable of CO2 transport, referred to as ‘COOporins’, are postulated to play a crucial role in leaf CO2 diffusion. However, the structural basis of CO2 permeation through aquaporins remains largely unknown.
Shaila Shermin Tania, Shigeko Utsugi, Yoshiyuki Tsuchiya, Shizuka Sasano, Maki Katsuhara, Izumi C. Mori   +5 more
wiley   +1 more source

Schrödinger's tree-On syntax and neural language models. [PDF]

Front Artif Intell, 2022
Kulmizev A, Nivre J.
europepmc   +1 more source

Interface Alterations in Cellulose Synthases Redefine CESA Complex Assembly to Enhance Cellulosic Biomass Production

GCB Bioenergy, Volume 17, Issue 7, July 2025.
We analyze sequence‐structure–function relationships, particularly interface mutations, in cellulose synthase (CESA) complexes (CSCs), which evolved from homomeric to heteromeric forms in seed plants. Heterologous expression of an evolutionarily divergent CESA minimizes interference with endogenous CSCs, promoting homomeric CSC formation and enhanced ...
Linfang Wei, Huiying Cui, Jiahui Bi, Xili He, Yajun Guan, Yunheng Zhou, Bingcheng Xu, Chuang Ma, Sheng‐You Huang, Shaolin Chen   +9 more
wiley   +1 more source

A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers

ChemBioChem, Volume 26, Issue 11, June 3, 2025.
This bacterial enzyme, cyclase‐phosphotriesterase (C‐PTE) from Ruegeria pomeroyi DSS‐3, shows significant potential for breaking down organophosphate pollutants. Beyond its capability to hydrolyze specific plasticizers such as triphenyl phosphate and tris(2‐chloropropyl) phosphate, C‐PTE's crystal structure reveals a binuclear zinc active site, and it ...
Dawei Ji, Rebecca L. Frkic, Javad Delyami, Joachim S. Larsen, Matthew A. Spence, Colin J. Jackson   +5 more
wiley   +1 more source

Engineering and Structural Elucidation of a Sac7d‐Derived IgG Fc‐Specific Affitin and Its Application for the Light‐Controlled Affinity Purification of Antibodies

ChemBioChem, Volume 26, Issue 11, June 3, 2025.
An affitin derived from the Sac7d scaffold enables the light‐controlled affinity purification of antibodies under physiological conditions, thus overcoming limitations of protein A chromatography. X‐ray crystallographic analysis and affinity measurements reveal complex formation with Fc at the CH2/CH3 junction, similar to protein A/G and FnRn. Combined
Felix Veitl, Andreas Eichinger, Peter Mayrhofer, Markus R. Anneser, Mauricio Testanera, Kilian Rauscher, Matthias Lenz, Arne Skerra   +7 more
wiley   +1 more source

Isoniazid‐Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity, and Cytotoxicity Investigations with Computational Validation

ChemMedChem, Volume 20, Issue 11, June 2, 2025.
Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar, Pule Seboletswe, Sahil Mishra, Neha Manhas, Safiyah Ghumran, Nagaraju Kerru, Françoise Roquet‐Banères, Maëlle Foubert, Laurent Kremer, Gaurav Bhargava, Parvesh Singh   +10 more
wiley   +1 more source

A Planck Radiation and Quantization Scheme for Human Cognition and Language. [PDF]

Front Psychol, 2022
Aerts D, Beltran L.
europepmc   +1 more source

Give Quantum Mechanics a Chance! [PDF]

, 2022
Eriksson, Karl-Erik
core  

COVID-19: Leaving lockdown-Of Schrodinger, cats, testing and masks. [PDF]

Int J Clin Pract, 2020
Thomson GA.
europepmc   +1 more source

Data science enabled discovery of a highly soluble 2,2'-bipyrimidine anolyte for application in a flow battery. [PDF]

Chem Sci, 2023
Pancoast AR, McCormack SL, Galinat S, Walser-Kuntz R, Jett BM, Sanford MS, Sigman MS.   +6 more
europepmc   +1 more source