Results 41 to 50 of about 91,891 (247)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Solving the Schrödinger equation with use of 1/N perturbation theory [PDF]

open access: yes, 1984
The large N expansion provides a powerful new tool for solving the Schrödinger equation. In this paper, we present simple recursion formulas which facilitate the calculation.
Mlodinow, Leonard D., Shatz, Michael P.
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Energy decay rate of multidimensional inhomogeneous Landau–Lifshitz–Gilbert equation and Schrödinger map equation on the sphere

open access: yesAdvances in Difference Equations, 2018
We consider the multidimensional dimensional inhomogeneous Landau–Lifshitz–Gilbert (ILLG) equation and its degenerate case, the Schrödinger map equation.
Penghong Zhong, Chao Zhang, Fengong Wu
doaj   +1 more source

Some Spectral Properties of Schrödinger Operators on Semi Axis

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2023
The main aim of this work is to investigate some spectral properties of Schrödinger operators on semi axis. We first present the Schrödinger equation with a piecewise continuous potential function q so that the problem differs from the classical ...
İbrahim Erdal
doaj   +1 more source

Strong confinement limit for the nonlinear Schrödinger equation constrained on a curve [PDF]

open access: yes, 2016
International audienceThis paper is devoted to the cubic nonlinear Schrödinger equation in a two dimensional waveguide with shrinking cross section.
Méhats, Florian, Raymond, Nicolas
core   +4 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Solving a nonlinear fractional Schrödinger equation using cubic B-splines

open access: yesAdvances in Difference Equations, 2020
We study the inhomogeneous nonlinear time-fractional Schrödinger equation for linear potential, where the order of fractional time derivative parameter α varies between 0 < α < 1 $0 < \alpha < 1$ .
M. Erfanian   +3 more
doaj   +1 more source

Infinite order symmetries for two-dimensional separable Schrödinger equations [PDF]

open access: yes, 2004
Consider a non-relativistic Hamiltonian operator H in 2 dimensions consisting of a kinetic energy term plus a potential. We show that if the associated Schrödinger eigenvalue equation admits an orthogonal separation of variables, there is a calculus to ...
Kalnins, Ernie G.   +2 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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