Results 141 to 150 of about 38,445 (215)

SKALE: An Interpretable Multiscale Machine Learning Model for Decoding Phase‐Specific Protein Aggregation in Neurodegenerative Proteinopathies

Aggregate, Volume 7, Issue 2, February 2026.
Protein aggregation drives diverse degenerative diseases, yet its molecular origins are difficult to predict. SKALE uses interpretable machine learning to link sequence, structure, and dynamics, revealing how local structural weakening triggers aggregation.
Wei Xuan Wilson Loo, Jia Shen Sio, Keyin Yap, Yan Shan Loo, Hui Xuan Lim, Shuangyue Zhang, Huitao Liu, Chen Seng Ng   +7 more
wiley   +1 more source

Entropic Dynamics Approach to Quantum Electrodynamics. [PDF]

Entropy (Basel)
Caticha A.
europepmc   +1 more source

Screw‐Dislocation‐Engineered Quantum Dot: Geometry‐Tunable Nonlinear Optics, Orbital Qubit Addressability, and Torsion Metrology

Annalen der Physik, Volume 538, Issue 2, February 2026.
A uniform torsion field—representing a controlled density of parallel screw dislocations—confines a single electron into a geometry‐defined quantum dot. In a perpendicular magnetic field, an Aharonov–Bohm flux breaks the m↔−m$m \leftrightarrow -m$ symmetry and yields a flux‐ and torsion‐tunable angular pseudospin (m=±1)$(m = \pm 1)$ with asymmetric ...
Edilberto O. Silva
wiley   +1 more source

Isoscattering non-isospectral quantum graphs. [PDF]

Sci Rep
Farooq O, Ławniczak M, Kurasov P, Sirko L.   +3 more
europepmc   +1 more source

HSD17B7 Counters Bone Loss in Estrogen Deficiency via Estrogen Receptor Stabilization and Mediates the Effect of Raloxifene

MedComm, Volume 7, Issue 2, February 2026.
In this study, we identified a previously unrecognized function of HSD17B7 as an ERα‐binding protein that serves as a coactivator to influence trabecular bone mass in estrogen deficiency. Specifically, deleting HSD17B7 in myeloid cells enhanced the number of osteoclasts and decreased trabecular bone mass post‐OVX, compared with control OVX, mirroring ...
Junyue Zhang, Yiping Song, Jeong‐Hyun Koo, Si Chen, Kyu Yun Jang, Sun‐Jung Yoon, Jung Ryul Kim, Young Jae Moon   +7 more
wiley   +1 more source

Carroll-Schrödinger equation as the ultra-relativistic limit of the tachyon equation. [PDF]

Sci Rep
Najafizadeh M.
europepmc   +1 more source

The many dimeric faces of Lys49 PLA2‐like proteins: Conformational plasticity and membrane binding drive functional dimer states

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Lys49 secreted phospholipase A2‐like proteins (sPLA2s) are major myotoxins in viperid snake venoms, causing rapid muscle damage in envenomation. Beyond their clinical relevance, these small non‐catalytic proteins provide a model to study how quaternary structure and conformational dynamics enable catalysis‐independent membrane disruption ...
Diane C. A. Lima, Vinicius Firmino dos Santos, Bernardo Rassi, Richard J. Ward, Thereza A. Soares   +4 more
wiley   +1 more source

One Dimensional Energy Cascades in a Fractional Quasilinear NLS. [PDF]

Arch Ration Mech Anal
Maspero A, Murgante F.
europepmc   +1 more source

Life on Mars? The physiological perspective

Experimental Physiology, EarlyView.
Ronan M. G. Berg, Damian M. Bailey
wiley   +1 more source

Role of the transmembrane domain in severe acute respiratory syndrome (SARS) coronavirus 2 spike for palmitoylation and membrane fusion

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Palmitoylation is a reversible post‐translational modification that enhances protein hydrophobicity and regulates cellular functions such as trafficking and signaling. In humans, this modification is catalyzed by 23 DHHC enzymes, but the mechanisms by which they recognize their substrates remain unclear.
Dina A. Abdulrahman, Michael Veit
wiley   +1 more source