Results 51 to 60 of about 179 (110)

Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways

ChemMedChem, EarlyView.
Compound 2, identified through in‐house screening and derived from SP18, exhibits high affinity for BAG3, as demonstrated by Surface Plasmon Resonance and docking studies. It induces a dose‐dependent proapoptotic response in HeLa cells, evidenced by increased Annexin V/PI staining, underscoring the triazole scaffold as a promising platform for BAG3 ...
Dafne Ruggiero, Eleonora Boccia, Emis Ingenito, Vincenzo Vestuto, Gilda D’Urso, Alessandra Capuano, Agostino Casapullo, Stefania Terracciano, Giuseppe Bifulco, Gianluigi Lauro, Ines Bruno   +10 more
wiley   +1 more source

Energy Landscapes in Chemical Reactions and Transport

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
Kinetics/dynamics of chemical reactivity and transport of chemical species in a solid are both determined by the energy landscape in which they take place. Discussing common grounds but also distinct differences may help in advancing the understanding in both fields.
Karl‐Michael Weitzel
wiley   +1 more source

STIP1 drives Metabolic Reprogramming in Esophageal Squamous Cell Carcinoma via AHCY‐LDHA Axis

Exploration, EarlyView.
A schematic model illustrating that LCA can inhibit ESCC growth by inhibiting the STIP1/AHCY/LDHA axis. In brief. Jin et al. demonstrated that targeting STIP1 can significantly inhibit the progression of esophageal squamous cell carcinoma. The high expression of STIP1 increased the interaction between AHCY and LDHA and then AHCY recruits PRMT3 to ...
Guoguo Jin, Yanming Song, Mingyang Yan, Shaobo Fang, Yang Shao, Kexin Zhao, Meng Liu, Qinxin Guo, Xinyang Jia, Chengjuan Zhang, Zhenwei Wang, Kangdong Liu, Xiang Li, Simin Zhao, Mee‐Hyun Lee, Zhiping Guo, Zigang Dong   +16 more
wiley   +1 more source

Primary care and the COVID-19 pandemic: Schrödinger's cat

ERJ Open Research, 2021
Emmanouil K Symvoulakis, Dimitrios Anyfantakis   +1 more
doaj   +1 more source

Agents and Responsibility Under the Many Worlds Interpretation of Quantum Mechanics [PDF]

, 2013
Bachelors Honours Thesis: Much philosophical thought has been given to the subject of personal identity. However, almost all of the discourse on personal identity seems to assume the Copenhagen Interpretation of ...
Firth, Steven J.
core  

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Metal‐Free Multicomponent Upcycling of Polybutadiene to Sulfonamide‐Functionalized Materials

Macromolecular Rapid Communications, EarlyView.
A catalyst‐free, one‐pot strategy enables the direct transformation of liquid polybutadiene into multifunctional materials through selective backbone editing and sulfonamide grafting. The resulting polymers exhibit tunable thermal and surface properties, as well as previously undocumented non‐conventional luminescence, expanding the functional ...
Janna Jeschke, Jan Hobich, Hatice Mutlu
wiley   +1 more source

Photon-assisted Landau-Zener transitions in driven few-level systems [PDF]

, 2019
I denne avhandlinga utforskar me Landau-Zener overgangar i drivne få-nivå system. Me behandlar drivingsfeltet både semi-klassisk (som ein tidsavhengig parameter i Hamilton operatoren) og heilt kvantemekanisk (som eit fotonfelt).
Lidal, Jonas
core  

The Design and Development of a Dexamethasone‐Tranfersome‐PF‐127/HA Stimuli‐Responsive Hydrogel for Intra‐Articular Therapy in Osteoarthritis

Nano Select, EarlyView.
A dexamethasone‐loaded transfersome‐based hydrogel was developed for sustained intra‐articular delivery in osteoarthritis. The system showed nanoscale particles size, high drug loading capacity, and shear‐thinning behavior. It enabled smooth injection, self‐healing, and prolonged drug release for up to 6 weeks.
Atang Motaung, Thankhoe A. Rants'o, Ravindra V. Badhe, Khonzisizwe Somandi, Yahya E. Choonara   +4 more
wiley   +1 more source

FROM SCHRÖDINGER’S CAT TOWARDS A QUANTUM APPROACH OF ACCOUNTING ESTIMATES, JUDGMENTS AND DECISION MAKING

Annals of the University of Oradea: Economic Science, 2016
Addressing regions competitiveness is relatively new in literature. The main cause of increasing interest for this concept is the development of the European Union put in a position to integrate, countries with different levels of development, formed themselves from regions heterogeneous in terms of economic efficiency.
openaire   +1 more source