Results 61 to 70 of about 4,189 (126)
Agents and Responsibility Under the Many Worlds Interpretation of Quantum Mechanics [PDF]
Bachelors Honours Thesis: Much philosophical thought has been given to the subject of personal identity. However, almost all of the discourse on personal identity seems to assume the Copenhagen Interpretation of ...
Firth, Steven J.
core
Chemical inhibition of K‐Ras posttranslational prenylation represents a promising strategy against aggressive cancers. A structure‐based design produces piperidine‐based peptidomimetics conjugated to cationic modules, effectively inhibiting FTase and GGTase I at single‐digit nanomolar concentrations.
Naomi Horiuchi+8 more
wiley +1 more source
The nRules that are developed in another paper are applied to two versions of the Schrodinger cat experiment. In version I the initially conscious cat is made unconscious by a mechanism that is initiated by a radioactive decay. In version II the initially unconscious cat is awakened by a mechanism that is initiated by a radioactive decay. In both cases
arxiv
Primary care and the COVID-19 pandemic: Schrödinger's cat
Emmanouil K Symvoulakis+1 more
doaj +1 more source
Asymptotically CAT(0) Groups [PDF]
We study the general theory of asymptotically CAT(0) groups, explaining why such a group has finitely many conjugacy classes of finite subgroups, is $F_\infty$ and has solvable word problem. We provide techniques to combine asymptotically CAT(0) groups via direct products, amalgams and HNN extensions.
arxiv
Small‐Molecule KRAS Inhibitors by Tyrosine Covalent Bond Formation
The development of the KRAS G12C inhibitor sotorasib was a major advance towards drugging KRAS. However, the G12C mutation is only found in about 10% of tumors with a KRAS mutation. KRAS tyrosine amino acids could provide alternative sites for covalent drug development.
Alexander Landgraf+5 more
wiley +1 more source
Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar+10 more
wiley +1 more source
On non-locally connected boundaries of CAT(0) spaces [PDF]
In this paper, we study CAT(0) spaces with non-locally connected boundary. We give some condition of a CAT(0) space whose boundary is not locally connected.
arxiv
Electrochemical Three‐component Synthesis of Alkenesulfonates from Cinnamic Acids, SO2, and Alcohols
An electrochemical three‐component synthesis of alkyl alkenesulfonates from cinnamic acids, SO2, and alkyl alcohols is reported. This metal‐free process employs inexpensive and readily available graphite electrodes in combination with easy‐to‐use stock solutions of SO2 and enables a straightforward decarboxylative preparation of styrene sulfonates via ...
Po‐Chung Chien+4 more
wiley +1 more source
Addressing regions competitiveness is relatively new in literature. The main cause of increasing interest for this concept is the development of the European Union put in a position to integrate, countries with different levels of development, formed themselves from regions heterogeneous in terms of economic efficiency.
openaire +1 more source