Results 81 to 90 of about 179 (110)

Amino Acid Substitutions in Loop C of Arabidopsis PIP2 Aquaporins Alters the Permeability of CO2

Plant, Cell &Environment, Volume 48, Issue 9, Page 6835-6846, September 2025.
ABSTRACT The transport of CO2 across biomembranes in plant cells is essential for efficient photosynthesis. Some aquaporins capable of CO2 transport, referred to as ‘COOporins’, are postulated to play a crucial role in leaf CO2 diffusion. However, the structural basis of CO2 permeation through aquaporins remains largely unknown.
Shaila Shermin Tania, Shigeko Utsugi, Yoshiyuki Tsuchiya, Shizuka Sasano, Maki Katsuhara, Izumi C. Mori   +5 more
wiley   +1 more source

Schlingensiefs Animatograph [PDF]

, 2008
Die vorliegende Arbeit beschreibt das künstlerische Langzeitprojekt „Der Animatograph“ von Christoph Schlingensief (geb. 1960), der sich als Film-, Theater- und Opernregisseur, Aktions- und bildender Künstler in verschiedenen künstlerischen Feldern ...
Berka, Roman Christian
core  

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, Volume 12, Issue 29, August 7, 2025.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Synthesis of New N,N′‐Diarylureas and Their Theoretical Study as Cannabinoid‐1 Receptor Inhibitors

ChemPlusChem, Volume 90, Issue 8, August 2025.
A series of new pyrazolo‐ and triazolo‐based N,N′‐diarylureas is synthesized following the triphosgene protocol in the last step. Density functional theory calculations and molecular docking provide strong evidence that all new compounds bind strongly to the cannabinoid‐1 (CB‐1) receptor, showing comparable results with the known allosteric CB‐1 ...
Eirini Tsemperlidou, Nikitas Georgiou, Demeter Tzeli, Nikolaos Karousis, George Varvounis   +4 more
wiley   +1 more source

Lithium and brain plasticity - studies on glial cell changes and electroconvulsive treatment-induced amnesia in rats [PDF]

, 2013
Depression and bipolar disorder, collectively known as mood disorders, are devastating, common and often chronic illnesses. Imaging studies of patients with mood disorders have demonstrated structural changes in several brain regions implicated in mood ...
Orre, Karin
core  

Decoding mEos4b day‐long maturation and engineering fast‐maturing variants

Protein Science, Volume 34, Issue 8, August 2025.
Abstract The maturation speed of fluorescent proteins is a crucial parameter that influences cellular brightness, effective labeling efficiency, and temporal resolution in fluorescence microscopy. Green‐to‐red photoconvertible fluorescent proteins (PCFPs) used in pulse‐chase experiments and super‐resolution techniques such as Photoactivated ...
Arijit Maity, Oleksandr Glushonkov, Isabel Ayala, Pascale Tacnet, Jip Wulffelé, Philippe Frachet, Bernhard Brutscher, Dominique Bourgeois, Virgile Adam   +8 more
wiley   +1 more source

z.B. Zeitschrift zum Beispiel Nummer 1 [PDF]

, 2018
Diese neue Zeitschrift soll dem Beispiel gewidmet sein – genauer: dem Beispielgebrauch. Wir benötigen und gebrauchen Beispiele. Das gilt – sobald wir etwas explizieren, veranschaulichen oder begründen wollen – für unseren alltäglichen Sprachgebrauch, für

core  

Nucleotide‐bound crystal structures of the SARS‐CoV‐2 helicase NSP13

Acta Crystallographica Section F, Volume 81, Issue 8, Page 338-347, August 2025.
Nucleotide‐bound crystal structures of SARS‐CoV‐2 NSP13 capture a state immediately following ATP hydrolysis and reveal how crystal packing can affect structure‐based drug design targeting NSP13.Nucleotide‐bound crystal structures of SARS‐CoV‐2 NSP13 in ADP‐ and ATP‐bound states were resolved to 1.8 and 1.9 Å, respectively. The ADP‐bound model captures
Patrick Kloskowski, Piotr Neumann, Annette Berndt, Ralf Ficner   +3 more
wiley   +1 more source

Computational and Experimental Druggability Assessment of Human DNA Glycosylases. [PDF]

ACS Omega, 2019
Michel M, Visnes T, Homan EJ, Seashore-Ludlow B, Hedenström M, Wiita E, Vallin K, Paulin CBJ, Zhang J, Wallner O, Scobie M, Schmidt A, Jenmalm-Jensen A, Warpman Berglund U, Helleday T.   +14 more
europepmc   +1 more source

Mathematics meets physics: A contribution to their interaction in the 19th and the first half of the 20th century [PDF]

, 2017
Es gibt wohl kaum Wissenschaftsgebiete, in denen die wechselseitige Beeinflussung stärker ist als zwischen Mathematik und Physik. Eine wichtige Frage ist dabei die nach der konkreten Ausgestaltung dieser Wechselbeziehungen, etwa an einer Universität ...
Schlote, Karl-Heinz, Schneider, Martina
core   +1 more source