Results 101 to 110 of about 67,419 (282)

The role of insulin-like growth factors signaling in merlin-deficient human schwannomas. [PDF]

, 2012
Loss of the tumor suppressor merlin causes development of the tumors of the nervous system, such as schwannomas, meningiomas, and ependymomas occurring spontaneously or as part of a hereditary disease Neurofibromatosis Type 2 (NF2).
Ammoun, S, Carroll, C, Ercolano, E, Hanemann, CO, Hilton, D, Ristic, N, Schmid, MC, Zhou, L   +7 more
core   +2 more sources

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

International Journal of Dermatology, EarlyView.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla, Zseraldin Metyovinyi, Fanni Adél Meznerics, Arash Mirzahosseini, Judit Tőke, Miklós Tóth, Henriett Butz, Attila Patócs, Márta Medvecz   +8 more
wiley   +1 more source

Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target [PDF]

, 2017
Loss or mutation of the tumour suppressor Merlin predisposes individuals to develop multiple nervous system tumours, including schwannomas and meningiomas, sporadically or as part of the autosomal dominant inherited condition Neurofibromatosis 2 (NF2 ...
Ammoun, Ammoun, Bian, Bretscher, Clark, Claudio, Cooper, Cox, Curto, Deevi, Dvorakova, Fevre-Montange, Flaiz, Flaiz, Fraenzer, Garcia-Rendueles, Gladden, Goutagny, Gronholm, Guerrero, Hanemann, Hanemann, Hebert, Huang, Huang da, James, Johnson, Kaempchen, Kang, Koschny, Lallemand, Lallemand, Lasonder, Lee, Li, Li, Li, Li, Loughran, Loughran, Magrassi, Maitra, Martin, Maudsley, McClatchey, McClatchey, McMahon, Meimoun, Mohler, Morrison, Morrow, Offenhauser, Pranjol, Puttmann, Qu, Rappsilber, Rouleau, Sakuda, Scherer, Schulze, Sharma, Sharma, Sheikh, Sun, Tanaka, Te Velthuis, Thang, Topolska-Wos, Torrado, Torres-Martin, Torres-Martin, Torres-Martin, Tyanova, van Tilborg, Wang, Weinman, Yang, Zhang, Zhao, Zhao, Zhou   +80 more
core   +4 more sources

Characterization of Oral Melanocytic Nevi in Sun‐Exposed and Sun‐Protected Regions

Oral Diseases, EarlyView.
ABSTRACT Objective Oral melanocytic nevi (OMN) are histologically similar to skin nevi; however, they are much rarer and not always related to sun exposure. This study aimed to characterize the histopathological, immunohistochemical, and molecular features of OMN in sun‐exposed (vermilion lip) and sun‐protected (intraoral) regions.
Thalita Soares Tavares, Adriana Aparecida Silva da da Costa, Marina Gonçalves Diniz, Daniela Pereira Meirelles, Sandra Beatriz Chaves Tarquínio, Ana Carolina Uchoa Vasconcelos, Aline Cristina Batista Rodrigues Johann, Ricardo Santiago Gomez, de Aguiar, Patrícia Carlos Caldeira   +9 more
wiley   +1 more source

Ancient schwannoma of thoracic spine in a schizophrenic patient with somatic delusion

Journal of Cancer Research and Practice, 2016
Ancient schwannoma is a rare variant of schwannoma characterized by histopathologic degenerative changes, which are thought to be the result of long-term tumor growth and aging. However, ancient schwannoma in the spinal canal is particularly rare.
Ya-Ting Wen, Li Wei, Tai-Ngar Lui
doaj   +1 more source

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. [PDF]

, 2016
BackgroundMalignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade.
Bernthal, Nicholas, Chmielowski, Bartosz, Crompton, Joseph G, Dry, Sarah, Eilber, Fritz C, Federman, Noah, Jensen, Sarah, Li, Yunfeng, Nelson, Scott, Shurell, Elizabeth, Singh, Arun S, Tumeh, Paul   +11 more
core   +2 more sources

Endoscopic Full‐thickness Resection for Gastric Submucosal Tumor: A Technical Analysis Study (With Video)

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background Endoscopic full‐thickness resection (EFTR) is an effective treatment method for gastric submucosal tumors (SMTs). We aimed to perform a technical analysis of EFTR in gastric SMT and compare it with the outcome parameters. Method Sixty‐one gastric SMTs from 60 patients were resected using EFTR. The indication criteria: size, 11–30 mm,
Hitoshi Mori, Noriya Uedo, Satoki Shichijo, Muneshin Morita, Yushi Kawakami, Yasuhiro Tani, Hiroyoshi Iwagami, Muneaki Miyake, Taro Iwatsubo, Minoru Kato, Shunsuke Yoshii, Takashi Kanesaka, Koji Higashino, Tomoki Michida, Ryu Ishihara, Naoki Shinno, Hisashi Hara, Yoshitomo Yanagimoto, Kazuyoshi Yamamoto, Takeshi Omori, Hitoshi Yoshiji   +20 more
wiley   +1 more source

Schwannoma of the cervical vagus nerve: A rare benign neurogenic tumor [PDF]

, 2013
A schwannoma, also known as an acoustic neuroma, is a benign nerve sheath tumor composed of schwann cells, which normally produce the insulating myelin sheath covering the peripheral nerves.
AKIN, Istemihan, ARIKOK, Ataturker, GUNSOY, Behcet, SAHAN, Mehmet, SIMSEK, Gokce   +4 more
core   +1 more source

Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells. [PDF]

, 2013
Loss of the Merlin tumour suppressor causes abnormal de-differentiation and proliferation of Schwann cells and formation of schwannoma tumours in patients with neurofibromatosis type 2.
Doddrell, RDS, Dun, X-P, Feltri, ML, Hanemann, CO, Parkinson, DB, Shivane, A, Sock, E, Wegner, M, Wrabetz, L   +8 more
core   +2 more sources

Decision‐making between DCA and VMAT in Linac‐based SRS for brain lesions: A dosimetric analysis based on tumor size and geometry and introduction of Qasym

Journal of Applied Clinical Medical Physics, Volume 26, Issue 11, November 2025.
Abstract Introduction Linac‐based SRS provides a highly precise noninvasive treatment option for intracranial lesions. DCA and VMAT are commonly used Linac‐based techniques. There are no standardized guidelines for technique selection, particularly considering the geometric properties of the lesions.
Lara Caglayan, Davide Scafa, Patrick Eich, Christina Leitzen, Fabian Kugel, Stephan Garbe, Gustavo Renato Sarria, Christos Moustakis, Dimos Baltas, Julian Philipp Layer, Cas Stefaan Dejonckheere, Andrea Renate Glasmacher, Shari Wiegreffe, Anca L Grosu, Eleni Gkika, Youness Nour   +15 more
wiley   +1 more source