Results 151 to 160 of about 70,444 (292)

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Ile/Ile homozygosity at codon 655 of HER2 in schwannoma

, 2013
Purpose: This study aimed to determine the genetic role of HER2, one of the epidermal growth factor receptor (EGFR) family, in schwannoma. The latter is a neogrowth of myelin-producing Schwann cells in peripheral nerves, inducible by N-nitrosoethylurea ...
Vin-Chi Wang; Jhy-Wei Li; Jeng-Hung Suen; Chuang, Tzu-Chao; Ming-Ching Kao
core   +1 more source

A case report of rectal schwannoma and literature review

结直肠肛门外科
Schwannoma is a rare tumor originating from Schwann cells, typically occurring in the peripheral nervous system. It is seldom found in the gastrointestinal tract and is particularly rare in the rectum. In recent years, with advances in imaging techniques,
Song Ziqiang, Qin Ping, Mou Chenghong, Zhou Chungen, Zhu Yong   +4 more
doaj   +1 more source

Schwannoma of the eyelid: Apropos of two cases

Indian Journal of Ophthalmology, 2009
Schwannoma, also referred to as neurilemmoma, is a benign tumor of peripheral nerve arising from Schwann cells that form the neural sheath. Schwannoma of ophthalmic interest is rare although it has been reported in relation with the orbit, and less ...
Touzri Raja, Errais Khalil, Zermani Rachida, Benjilani Sarra, Ouertani Amel   +4 more
doaj  

The tumour immune microenvironment is enriched but suppressed in vestibular schwannoma compared to meningioma: therapeutic implications for NF2-related schwannomatosis

Acta Neuropathologica Communications
Currently there are no therapeutic agents that are effective against both vestibular schwannoma and meningioma, the two most common tumour types affecting patients with the rare tumour predisposition syndrome NF2-related schwannomatosis. This study aimed
Grace E. Gregory, Michael J. Haley, Adam Paul Jones, Leo A. H. Zeef, D. Gareth Evans, Andrew T. King, Pawel Paszek, Kevin N. Couper, David Brough, Omar N. Pathmanaban   +9 more
doaj   +1 more source

Anesthetic management of schwannoma mimicking carotid body tumor

, 2012
Chitra SivasankarDepartment of Anesthesiology, Guthrie Clinic, Sayre, PA, USAAbstract: Schwannomas are rare and slow-growing neurogenic tumors for which surgery is the standard of care.
Sivasankar C
core  

A case of plexiform schwannoma arising from the sciatic, tibial, and peroneal nerves

Radiology Case Reports
Plexiform schwannoma is a rare subtype of schwannoma. In this report, we present a case of plexiform schwannoma arising from the sciatic, tibial, and peroneal nerves.
Shuhei Miyamoto, MD, Ryo Takaji, MD, Norimasa Kaneko, MD, Tatsuya Iwasaki, MD, Masanori Kawano, MD, Kazuhiro Tanaka, MD, Tsutomu Daa, MD, Yoshiki Asayama, MD   +7 more
doaj   +1 more source

Vestibular Schwannoma: Can Circulating Inflammatory Markers Predict Tumor Growth?

openObiettivo: Valutare la capacità dei marcatori infiammatori circolanti di predire la crescita dello Schwannoma vestibolare, per selezionare in fase precoce di malattia i pazienti candidati al trattamento attivo. Metodi: Studio retrospettivo eseguito
KATZMAN, HAGAR
core  

Meu Schwannoma Vestibular. O dia em que minha vida mudou

, 2014
The story describes the impact of a diagnosis on the author’s life: Vestibular schwannoma (also known as acoustic neuroma). From that moment, all the quotidian, the relative quiet of the daily routine and the prioritization of needs experienced a ...
Aznar, Juan Antonio
core  

Hybrid Schwannoma/Neurofibroma of the Neck: A Case Report

Ear, Nose & Throat Journal
Neck hybrid schwannoma/neurofibromas are uncommon and classified as peripheral nerve sheath tumors (PNSTs). PNSTs develop from soft tissues, of which schwannoma, perineurioma, and neurofibroma are the most common. Hybrid PNSTs consist of more than 1 type
Wei-Ting Kao MD, Chia-Ying Chu MD, Kuang-Hsuan Shen MD   +2 more
doaj   +1 more source