Results 101 to 110 of about 4,213 (222)

A Case of Hybrid Cellular Neurothekeoma and Perineurioma With a Folliculin Gene Mutation

Journal of Cutaneous Pathology, Volume 52, Issue 5, Page 374-378, May 2025.
ABSTRACT Hybrid peripheral nerve sheath tumors (PNSTs) are benign tumors that show features of more than one type of PNST. Benign cutaneous plexiform hybrid tumor of perineurioma and cellular neurothekeoma (BCPHTPCN) is a rare, recently described entity that shows various combinations of histomorphologic and immunophenotypic features of the PNSTs ...
Taylor J. Prechtel, Emma Brashear, Carina A. Dehner, Ahmed K. Alomari   +3 more
wiley   +1 more source

PMDA Perspective on Use of Real‐World Data and Real‐World Evidence as an External Control: Recent Examples and Considerations

Clinical Pharmacology &Therapeutics, Volume 117, Issue 4, Page 910-919, April 2025.
Recent discussions about the utilization of real‐world data (RWD) and real‐world evidence (RWE) have been more focused on drug development for regulatory approval rather than during the post‐marketing stage. In Japan, RWD/RWE have been practically utilized as an external control for drug approval.
Junichi Asano, Hiromi Sugano, Hiroyuki Murakami, Atsushi Noguchi, Yuki Ando, Yoshiaki Uyama   +5 more
wiley   +1 more source

Simple schwannomatosis or an incomplete Coffin-Siris? Report of a particular case

eNeurologicalSci, 2019
Background: Schwannomatosis is a genetic disorder that belongs to NF family. The mutation of SMARCB1 gene has been related to this entity and Coffin-Siris syndrome, as well. We reported a case of a female patient with SMARCB1 mutation who has developed a
G. Bellantoni, F. Guerrini, M. Del Maestro, R. Galzio, S. Luzzi   +4 more
doaj   +1 more source

A possible cause of misdiagnosis in tumors of the axilla: schwannoma of the brachial plexus [PDF]

, 2008
The Authors report a rare case of a 57 years old man affected by a left radial nerve schwannoma that occurred as an asymptomatic lesion of the axilla. At clinical examination the lump was undistinguishable from the most common axillary lymphadenopathy. A
Briganti M, Ceci F, Cipriani B, De Angelis F, DERIU, GLORIA, Di Filippo A, Martellucci A, Nicodemi S, Picchio M, SPAZIANI, Erasmo, Stagnitti F., VITOLO, Domenico   +11 more
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Why Consider Aspirin for the Treatment of Vestibular Schwannoma? A Brief Review and Randomized, Double‐Blind, Placebo‐Controlled Study Proposal

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 2, April 2025.
This article reviews the data for and against the use of aspirin to prevent the growth of vestibular schwannomas. It then proposes a randomized placebo‐controlled double‐blinded study to clarify contradictory retrospective findings. ABSTRACT Objective The primary objective of this study is to review the evidence for aspirin use to prevent the growth of
D. Bradley Welling, Brian A. Neff, Fred F. Telischi, Neil Patel, Konstantina M. Stankovic   +4 more
wiley   +1 more source

Primary Tracheal Schwannoma With Extension to the Thyroid Gland: Management

Clinical Case Reports, Volume 13, Issue 1, January 2025.
ABSTRACT The occurrence of neurogenic tumors in the tracheobronchial tree is uncommon. We report a case of transmural tracheal schwannoma with extraluminal component extending upto the left thyroid lobe. 40‐year‐old male presented with scanty hemoptysis due to transmural tracheal schwannoma with extraluminal part of tumor extending till the left lobe ...
Srijana Thapa, Ranjan Sapkota, Srijana Khati, Aayush Adhikari   +3 more
wiley   +1 more source

Genetic Landscape of a Pleural Mesothelioma in a Child Affected by NF2-Related Schwannomatosis. [PDF]

Int J Mol Sci
We report the first case of pleural mesothelioma (PM) occurring in a child affected by NF2-related schwannomatosis (NF2-SWN) and without any history of environmental exposure to asbestos.
Ognibene M, Piccolo G, Crocco M, Di Duca M, Verrico A, Molteni M, Romano F, Capra V, Rossi A, Zara F, De Marco P, Milanaccio C.   +11 more
europepmc   +2 more sources

Multiple spinal nerve sheath tumors in a dog resembling schwannomatosis in humans. [PDF]

J Vet Diagn Invest
A 7-y-old male neutered crossbreed dog was presented to a veterinary referral hospital with a 9-mo history of progressive non-ambulatory tetraparesis. A magnetic resonance imaging (MRI) study revealed multiple T2-weighted hyperintense intradural nodular ...
Tse JL, Rebollada-Merino A, Pumarola M, Ortiz AL, Toni C.   +4 more
europepmc   +2 more sources

Schwannomatosis [PDF]

Neurology, 2008
Alexey, Surov, Malte, Kornhuber, Curd, Behrmann   +2 more
openaire   +2 more sources

Functional regulation of the Neurofibromatosis 2 tumor suppressor merlin [PDF]

, 2011
Neurofibromatosis 2 (NF2) is an autosomal dominant disorder manifested by the formation of multiple benign tumors of the nervous system. Affected individuals typically develop bilateral vestibular schwannomas which lead to deafness and balance disorders.
Pehrsson, Minja
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