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Molecular Studies on Schwannomatosis
2008Schwannomatosis is a genetic disease characterized by multiple non-vestibular schwannomas with an unknown genetic cause. One recent study suggested that schwannomatosis may be as common as neurofibromatosis type 2. Schwannomatosis and NF2 share common clinical and molecular features, but at the same time differ fundamentally from one another.
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[Neurofibromatosis versus schwannomatosis].
Fortschritte der Neurologie-Psychiatrie, 1998Neurofibromatosis Type 1 and 2 (NF1 und NF2) are different forms of neurofibromatosis, well defined both clinically and genetically. In absence of typical clinical features of NF1 (café-au-lait-spots, cutaneous neurofibromas, Lisch-nodules) or NF2 (vestibular schwanoma) clinical classification is often not possible. Neurofibromas are more common in NF1
V F, Mautner +4 more
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Clinical epidemiology of NF2-related schwannomatosis
The epidemiology of NF2-related schwannomatosis (NF2) has only been possible to delineate after the separation of NF2 from the more common nerve sheath-predisposing tumor condition NF1 in 1987. Two groups have published data on the birth incidence and prevalence of NF2 in the United Kingdom and Finland.D Gareth, Evans, Scott R, Plotkin
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