Results 71 to 80 of about 1,956 (168)

Sporadic NF2 Mosaic: Multiple spinal schwannomas presenting with severe, intractable pain following pregnancy

Interdisciplinary Neurosurgery, 2017
The aim of the present paper is to report undiagnosed sporadic neurofibromatosis type 2 presenting with symptomatic compressive spinal tumors following pregnancy.
Jeffrey H. Zimering, Bryan D. Choi, Matthew J. Koch, John C. Dewitt, Anat Stemmer-Rachamimov, John H. Shin   +5 more
doaj   +1 more source

Pain correlates with germline mutation in schwannomatosis

Medicine, 2018
Schwannomatosis has been linked to germline mutations in the SMARCB1 and LZTR1 genes, and is frequently associated with pain.In a cohort study, we assessed the mutation status of 37 patients with clinically diagnosed schwannomatosis and compared to clinical data, whole body MRI (WBMRI), visual analog pain scale, and Short Form 36 (SF-36) bodily pain ...
Jordan, Justin, Cai, Wenli, Harris, Gordon, Bredella, Miriam, Gusella, James, Plotkin, Scott, Smith, Miriam J., Walker, James A., Erdin, Serkan, Talkowski, Michael E., Merker, Vanessa L., Ramesh, Vijaya, Seijo, Marlon, Suuberg, Alessandra   +13 more
openaire   +5 more sources

A single-cell atlas of Schwannoma across genetic backgrounds and anatomic locations

Genome Medicine
Background Schwannomas are nerve sheath tumors arising at cranial and peripheral nerves, either sporadically or in patients with a schwannomatosis-predisposition syndrome. There is limited understanding of the transcriptional heterogeneity of schwannomas
L. Nicolas Gonzalez Castro, Avishai Gavish, Lillian Bussema, Christopher W. Mount, Cyril Neftel, Masashi Nomura, E. Antonio Chiocca, Wenya Linda Bi, Omar Arnaout, Fred G. Barker, Justin M. Brown, Justin T. Jordan, Tracy T. Batchelor, Anat Stemmer-Rachamimov, Scott R. Plotkin, Itay Tirosh, Mario L. Suvà   +16 more
doaj   +1 more source

Historical Development of Diagnostic Criteria for NF2-related Schwannomatosis

Neurologia Medico-Chirurgica
NF2-related schwannomatosis (NF2; previously termed neurofibromatosis type 2) is a tumor-prone disorder characterized by development of multiple schwannomas and meningiomas. The diagnostic criteria of NF2 have been regularly revised.
Ryota TAMURA, Masahiro YO, Masahiro TODA
doaj   +1 more source

Oral plexiform schwannoma: A case report and relevant immunohistochemical investigation

SAGE Open Medical Case Reports, 2019
Schwannomas are benign peripheral nerve sheath tumors originating from the Schwann cells. Most schwannomas in the head and neck region are solitary; however, multiple schwannomas affecting one or more nerves suggest a possible association with ...
Johan Sergheraert, Dominique Zachar, Vincent Furon, Roman-Hossein Khonsari, Nicolas Ortonne, Cedric Mauprivez   +5 more
doaj   +1 more source

Sciatic Schwannoma: A Rare Cause of Sciatica and its Surgical Management

Journal of Clinical and Diagnostic Research
Schwannoma are rare benign tumours of the peripheral nerve sheath, arising from the schwann cells. Sciatic nerve is the largest nerve of the human body, and sciatic schwannoma are rare, with incidence of
Saurabh Gawand, Rajesh Gattani, Arvind Chava, Apoorva Pande, Abhiram Chadive   +4 more
doaj   +1 more source

Age-related schwannomatosis with potential exosome-mediated contribution to prostate hyperplasia: a case report and mini-review

Therapeutic Advances in Urology, 2019
A 72-year-old Caucasian man incurring a prostate hypertrophy presented with a right forearm nodule, the growth of which appeared to parallel the rise in his blood prostate-specific antigen (PSA) level. Echographic examination was consistent with a median-
Bérengère Chignon-Sicard, Véronique Hofman, Daniel Chevallier, Jean-Michel Cucchi, Marius Ilié, Bérengère Dadone-Montaudié, Florence Paul, Xavier Carpentier, Hervé Quintens, Coraline Bence-Gauchiez, Didier Caselles, Jacqueline Rossant, Matthieu Durand, Roger Bertolotti   +13 more
doaj   +1 more source

Trigeminal Neuralgia with Persistent Trigeminal Artery Variant and Schwannomatosis of the Abducens and Lower Cranial Nerves: A Case Report

Journal of the Korean Society of Radiology
Multiple cranial neuropathies are complex neurological disorders that present significant treatment challenges due to their intricate and multifaceted underlying causes.
Seong Gwang Kim, Hye Jeong Choi, Kyung Gi Cho, Jung Youn Kim, Sang Heum Kim   +4 more
doaj   +1 more source

Schwannomatosis [PDF]

, 2020
openaire   +2 more sources

Genetic Basis and Clinical Management of Schwannomatosis

Journal of Korean Neurosurgical Society
Schwannomatosis (SWN) is now recognized as a broad classification that includes neurofibromatosis (NF) type 2, reflecting their shared genetic and phenotypic characteristics. Previously, SWN and NF type 2 were considered distinct clinical entities; however, the 2022 classification revision has unified them under the umbrella of SWN, with NF type 2 now ...
Shohei Nagasaka, Ji Hoon Phi
openaire   +2 more sources