Results 51 to 60 of about 17,169 (214)

Lifespan Pancreas Morphology for Control Versus Type 2 Diabetes Using AI on Largescale Clinical Imaging. [PDF]

Clin Anat
ABSTRACT Understanding how pancreas size and shape change with normal aging is critical for establishing a baseline to detect deviations in type 2 diabetes and other pancreatic disease. We measure pancreas size and shape using morphological measurements from early development through aging (ages 0–90).
Remedios LW, Cho C, Schwartz TM, Su D, Rudravaram G, Gao C, Krishnan AR, Saunders AM, Kim ME, Bao S, Lasko TA, Powers AC, Landman BA, Virostko J.   +13 more
europepmc   +2 more sources

Evolutionary morphology of the haplorhine hamate

The Anatomical Record, EarlyView.
Abstract Primates adopt a variety of hand postures during an impressive diversity of locomotor and manipulative behaviors. Morphological research has found that elements of the hand skeleton, such as the hamate, hold key information for inferring hand use and locomotor kinematics in extinct species.
Laura E. Hunter, Matthew W. Tocheri, Caley M. Orr, Biren A. Patel, Zeresenay Alemseged   +4 more
wiley   +1 more source

Osteohistological evidence for terrestrial adaptation and an extended growth period in mekosuchine crocodylians and its potential role in their extinction

The Anatomical Record, EarlyView.
Abstract The Australasian crocodylian fossil record is dominated by the extinct endemic clade Mekosuchinae, with known members spanning the Eocene‐to‐Holocene. This diverse clade exhibited high morphological disparity, from early members superficially similar to Crocodylus, to more terrestrial forms later in the clade's evolutionary history.
Devin K. Hoffman, Cecily S. C. Nicholl, Oliver Bradley, Sreya Magar, Marie Sofia Sebaratnam, Alexandra Houssaye, Ryan N. Felice, Adam M. Yates, Stephen F. Poropat, Philip D. Mannion   +9 more
wiley   +1 more source

Cefepime exposure in prolonged or intermittent infusion in critically ill children

British Journal of Clinical Pharmacology, EarlyView.
Aims Cefepime is commonly used in critically ill children for whom there is a high between‐subject variability. To reach the therapeutic pharmacokinetic (PK) target in critically ill patients, prolonged infusion of beta‐lactams seems to be the most efficient.
Marc Hobeika, Deborah Hirt, Emmanuelle Bille, Sihem Benaboud, Julie Toubiana, Pierre‐Louis Léger, Jérôme Rambaud, Agathe Béranger, Delphine Callot, Sylvain Renolleau, Jean‐Marc Treluyer, Mehdi Oualha, Noémie de Cacqueray   +12 more
wiley   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

On the Duality of Discrete and Periodic Functions

Mathematics, 2015
Although versions of Poisson’s Summation Formula (PSF) have already been studied extensively, there seems to be no theorem that relates discretization to periodization and periodization to discretization in a simple manner.
Jens V. Fischer
doaj   +1 more source

Population pharmacokinetics of levetiracetam in term neonates with hypoxic–ischemic encephalopathy and therapeutic hypothermia: The LEVNEONAT‐1 study

British Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to describe the pharmacokinetics (PK) of levetiracetam (LEV) in term neonates treated for neonatal seizures secondary to hypoxic–ischemic encephalopathy (HIE). Methods Fifteen neonates were included and received a loading dose ranging from 30 to 60 mg/kg followed by eight maintenance doses corresponding to one‐fourth of the loading
Léo Mimram, Moreno Ursino, Julie Leger, Emilie Bourrel‐Ponchel, Florence Flamein, Alexandra Chadie, Isabelle Guellec, Sarah Zohar, Vincent Jullien, Géraldine Favrais   +9 more
wiley   +1 more source

Evidence for adaptive explanations of semelparity in animals

Biological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher, Roberto Salguero‐Gómez   +1 more
wiley   +1 more source

The influence of circadian variables on ecotoxicology metabolomics

Biological Reviews, EarlyView.
ABSTRACT Ecotoxicologists are using metabolomics increasingly to gain insight into toxicological mechanisms and sublethal effects of chemical exposures. Metabolomics offers a sensitive multi‐parameter approach that can detect biochemical responses not obvious using apical and behavioural endpoints.
Ryan I. Lester, David J. Beale, Anthony R. Carroll, Steven D. Melvin   +3 more
wiley   +1 more source

Distribution Approach to Local Volatility for European Options in the Merton Model with Stochastic Interest Rates

Entropy
The Dupire formula is a very useful tool for pricing financial derivatives. This paper is dedicated to deriving the aforementioned formula for the European call option in the space of distributions by applying a mathematically rigorous approach developed
Piotr Nowak, Dariusz Gatarek
doaj   +1 more source