Results 141 to 150 of about 146,536 (233)

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Biological variation of baseline serum cortisol concentration in healthy dogs, part 2: clinical applications. [PDF]

Front Vet Sci
Wicker S, Craig S, Albright JD, Springer C, Freeman K, Giori L.   +5 more
europepmc   +1 more source

Physics‐Informed Generative Machine Learning for Designing Crack‐Free γ′‐Strengthened Ni‐Based Superalloys for Laser Powder Bed Fusion

Materials Genome Engineering Advances, EarlyView.
This research proposes a physics‐informed generative machine learning framework to design SHA800, a crack‐free γ′‐strengthened nickel‐based superalloy for laser powder bed fusion, achieving a 43% γ′ volume fraction and 587 HV0.2 hardness. ABSTRACT Fabricating γ′‐strengthened nickel‐based superalloys via laser powder bed fusion (LPBF) faces significant ...
Kai Guo, Dongwei Guan, Tao Hu, Yaqing Hou, Xiaoqun Li, Zhongnan Bi, Songzhe Xu, Hao Yu, Wei Xu, Weidong Xuan, Chaoyue Chen, Zhongming Ren   +11 more
wiley   +1 more source

Highly Cited Dental Implant Research: A Bibliometric Analysis of Publication Patterns and Research Themes. [PDF]

Healthcare (Basel)
Ho YS, Grigoriadis A, Christidis N, Grigoriadis J.   +3 more
europepmc   +1 more source

Utility of Pelvic Floor Therapy and Behavioral Interventions in the Neurogenic Lower Urinary Tract Dysfunction (NLUTD) Population

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Neurogenic lower urinary tract dysfunction (NLUTD) describes a wide range of symptoms depending on neurologic diagnosis and the resulting bladder and sphincter dysfunction. This narrative review is designed to address the question regarding which NLUTD population benefits most from pelvic floor therapy and behavioral interventions, and ...
Sara M. Lenherr
wiley   +1 more source

Intravenous administration of ex vivo expanded human umbilical cord blood-derived CD34⁺ cells in a preterm hypoxic-ischemic encephalopathy mouse model. [PDF]

Sci Rep
Arai N, Tanaka E, Ohnishi S, Hamazaki T.
europepmc   +1 more source

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang, William I. Jaffe, Ariana L. Smith   +2 more
wiley   +1 more source

Intravascular ultrasound wall shear stress imaging in stented coronary arteries with ultrafast Doppler. [PDF]

Sci Rep
Singh TC, Strassle Rojas S, Shah I, Martín Tempestti J, Veneziani A, Lindsey BD.   +5 more
europepmc   +1 more source

The Interpretability of the Neurogenic Bladder Symptom Score

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To define mild, moderate and severe symptom categories of the neurogenic bladder symptom score (NBSS) and NBSS‐short form (SF), and to calculate the minimal clinically important difference (MCID) of the NBSS‐SF. Methods We used existing datasets from the original NBSS validation study (n = 230 patients with spinal cord injury (SCI ...
Jeremy Dai, Erica Li, Rose Khavari, Jorge Moreno‐Palacios, Cristiano M. Gomes, Jeremy Myers, John T. Stoffel, Sean Elliott, Sara M. Lenherr, Blayne Welk   +9 more
wiley   +1 more source

Theses on Healthcare-Associated Infections and Their Publication Conversion Rates. [PDF]

Infect Dis Clin Microbiol
Arslan M, Karakök T, Akgül F, Batırel A, Keske Ş, Ergönül Ö.   +5 more
europepmc   +1 more source