Results 181 to 190 of about 146,536 (233)

Benzene at 200: from a simple ring to a universe of fused aromatic carbon. [PDF]

Chem Sci
Martín N, Feringa BL.
europepmc   +1 more source

FDX1 Depletion Activates CD8+ T Cell Antitumor Immunity by Promoting DMBT1 Secretion in Cuproptosis of Colorectal Cancer

Cancer Science, EarlyView.
Elesclomol‐induced cuproptosis potently activates both innate and adaptive antitumor immunity, especially CD8+ T cell immunity. FDX1 serves as a central regulator of CD8+ T cell functionality through DMBT1 downregulation during cuproptosis in colorectal cancer.
Jieqiong Wu, Zaixi Lian, Mingzhou Li, Xingtu Qin, Xiaoyu Lei, Lihua Yang, Lin Bing, Qiuyue Li, Lingyan Zhou, Zhiyang Ma, Xuemei Xu, Jinghao Huang, Zilong Chen, Lijie Chen, Lingjie Zhang, Zhiyuan Xiao, Xiangyu Jian, Xiaoqin Zhang, Yanqing Ding, Yaping Ye, Li Liang, Hongli Jiao, Shuyang Wang   +22 more
wiley   +1 more source

Scalable Computation of Topological Abstractions for Scalar Data

Computer Graphics Forum, EarlyView.
Abstract Topological data analysis has become an important tool for large scale scalar data analysis and visualization, efficiently extracting the inherent structure and features of interest of the data. However, with growing dataset sizes and complexity, it is increasingly becoming infeasible to compute topological abstractions of interest in serial ...
M. Will, J. Lukasczyk, J. Tierny, A. Gyulassy, G. H. Weber, H. Carr, C. Garth   +6 more
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, EarlyView.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Cellular and Molecular Mechanisms Regulating Neuronal Function, Homeostasis, and Disease. [PDF]

Brain Sci
Sobral AF, Barbosa DJ.
europepmc   +1 more source

Decoverslipping of Archival Cytology Aspirate Smears for Ancillary Studies: A Review of Methods and Institutional Experience With Freezer‐Based Techniques

Cytopathology, EarlyView.
Freezer‐based decoverslipping of archival cytology aspirate smears achieved only 32.5% slide‐level success (26/80), with mounting medium composition and coverslip material, not freezing temperature or duration, identified as dominant determinants, underscoring the need to align coverslipping practices with anticipated ancillary testing requirements ...
Nyein Nyein Htun, Sinchita Roy‐Chowdhuri, Benjamin B. Morris, Gloria Hopkins Sura   +3 more
wiley   +1 more source

Attractiveness of Melon Genotypes to Whitefly (Bemisia tabaci) Mediated by Foliar Morphological and Biochemical Traits

Entomologia Experimentalis et Applicata, EarlyView.
This study identifies melon genotypes resistant to Bemisia tabaci by integrating morphological and biochemical leaf traits. Using free‐choice and no‐choice assays, we demonstrate that resistance is primarily mediated by antixenosis. Genotypes CNPH 11‐1071‐43, CNPH 06‐1047‐343, CNPH 13‐1076, and BG MEL 16 significantly reduced whitefly settling and ...
Lucas de Lima Farias, Wenner Vinícius Araújo Saraiva, Lincon Matheus Araújo Silva, Karen Alessandra Castro Ramos, Vanessa de Araújo Lira, Gabriela Priscila de Sousa Maciel, Celli Rodrigues Muniz, Nívia da Silva Dias‐Pini   +7 more
wiley   +1 more source

Retracted: Impact of Pulsed Electric Field Ablation on His Bundle Conduction: A Preclinical Canine Study. [PDF]

Med Sci Monit
Zhai Z, Wang Y, Shi L, Liu X.
europepmc   +1 more source

Exploiting Native Biodiversity for Invasive Species Management: The Case of Exorista larvarum as a Natural Enemy of the Invasive Box Tree Moth Cydalima perspectalis

Entomologia Experimentalis et Applicata, EarlyView.
The investigations evaluated the performance of the native parasitoid Exorista larvarum (L.) on last instar Cydalima perspectalis (Walker) larvae, using the factitious host Galleria mellonella (L.) as a control. Laboratory bioassays were conducted using no‐choice and choice (1:1 and 5:5) experimental designs.
Serena Gallizia, Santolo Francati, Maria Luisa Dindo, Chiara Ferracini   +3 more
wiley   +1 more source