Results 131 to 140 of about 404 (147)

Protective Effect of Sciadopitysin against Isoproternol-Induced Myocardial Infarction in Rats

Pharmacology, 2019
The current study enumerates the beneficial role of sciadopitysin (SDN) against isoproternol (ISO)-induced myocardial infarction (MI) in rats. The MI was experimentally induced via subcutaneous injection of ISO in experimental rats. SDN showed to prevent myocardial necrosis via reducing the levels of creatine kinase-MB and lactate dehydrogenase ...
Yuhua, Cai, Yunpeng, Li
openaire   +2 more sources

Antioxidant Activity and Lifespan-Extending Effects of Sciadopitysin Isolated from Ginkgo biloba Leaves in Caenorhabditis elegans

Saeng'yag haghoeji
junhyeong kim
exaly   +2 more sources

Medicinal Importance and Pharmacological Activities of Sciadopitysin in the Medicine: Drug Target for Neuroprotection, Myocardial Infarction, Alzheimer’s Disease, Diabetes, and Related Complications

Current Functional Foods, 2023
Backgrounds: Herbal medicines have been used in the medicine over the last three decades and demand of herbal drugs has been increasing in the modern medicine due to their health beneficial aspects and pharmacological activities. Herbal medicines were mainly derived from the plants and their derived products which have significant role in the ...
Kanika Patel, Dinesh Kumar Patel
openaire   +1 more source

Sciadopitysin: active component fromTaxus chinensisfor anti-Alzheimer's disease

Natural Product Research, 2013
Five taxane diterpenoids derived from the 95% ethanol extract of Taxus chinensis were tested for the inhibitory activities on amyloid-beta (Aβ) peptide aggregation. Using thioflavin-T fluorescence assay, sciadopitysin was found to exhibit the most potency against Aβ aggregation and the formation of fibrils.
Qiong, Gu, Yanping, Li, Yingchun, Chen, Peifen, Yao, Tianmiao, Ou   +4 more
openaire   +2 more sources

Sciadopitysin mitigates spermatological and testicular damage instigated by paraquat administration in male albino rats.

Scientific reports, 2023
Paraquat (PQ) is a herbicide that has ability to induce testicular toxicity by producing reactive oxygen species (ROS). Sciadopitysin (SPS) is a promising flavonoid that displays multiple pharmacological properties i.e., anti-inflammatory, anti-oxidant and anti-apoptotic.
Muhammad Umar, Ijaz, Mohammad, Qamer, Ali, Hamza, Hussain, Ahmed, Tayyaba, Afsar, Mahmoud, Abulmeaty, Arusha, Ayub, Suhail, Razak   +7 more
openaire   +1 more source

[Inhibition of sciadopitysin against UDP-glucuronosyltransferases].

Yao xue xue bao = Acta pharmaceutica Sinica, 2018
This study was designed to investigate the inhibitory effects of sciadopitysin on the catalytic activities of human 12 kinds of UDP-glucuronosyltransferases (UGTs) in vitro. The risk of drug-drug interactions (DDI) is predicted by in vitro-in vivo extrapolation (IV-IVE).
Xin-xin, Wang, Jie, Hou, Jing, Ning, Yong-qiang, Pan, Mo, Hong, Bin, Guo   +5 more
openaire   +1 more source

Protective effects of sciadopitysin against methylglyoxal‐induced degeneration in neuronal SK‐N‐MC cells

Journal of Applied Toxicology, 2022
Kwang Sik Suh, Suk Chon, Eun Mi Choi
exaly  

Medicinal Importance and Pharmacological Activities of Sciadopitysin in the Medicine: Drug Target for Neuroprotection, Myocardial Infarction, Alzheimer’s Disease, Diabetes, and Related Complications

Current Functional Foods, 2022
Dr. Dinesh Kumar Patel
exaly  

Biological importance and therapeutic benefit of sciadopitysin on Myocardial infarction: Biological application of creatine kinase and lactate dehydrogenase in the medicine

Metabolism, 2022
openaire   +1 more source

Sciadopitysin from Taxus chinensis as a potential therapeutic agent for Huntington’s disease

Natural Product Research
Taniya Mary, Martin, Ajay, Guru
openaire   +2 more sources