Results 111 to 120 of about 220,539 (258)

Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice [PDF]

, 2018
Elevated N-methyl-D-aspartate receptor (NMDAR) activity is linked to central sensitization and chronic pain. However, NMDAR antagonists display limited therapeutic potential because of their adverse side effects. Novel approaches targeting the NR2B-PSD95-
Chawla, Aarti, Courtney, Michael J., Hohmann, Andrea G., Hudmon, Andy, Lai, Yvonne Y., Lee, Wan-Hung, Li, Li-Li   +6 more
core   +1 more source

Differential expression of neuregulin-1 isoforms and downregulation of erbin are associated with Erb B2 receptor activation in diabetic peripheral neuropathy [PDF]

, 2013
BACKGROUND: Aberrant neuron/glia interactions can contribute to a variety of neurodegenerative diseases and we have previously demonstrated that enhanced activation of Erb B2, which is a member of the epidermal growth factor receptor (EGFR) family, can ...
Pan Pan, Rick T Dobrowsky
core   +1 more source

Investigating the mechanical behaviour at a core-sheath interface in peripheral nerves [PDF]

, 2002
Published without an ...
Afoke, A., Brown, R.A., Phillips, J.B., Tillett, R.L.   +3 more
core  

Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome [PDF]

, 2017
Rett syndrome (RTT) is a neurological disorder characterized by motor and cognitive impairment, autonomic dysfunction and a loss of purposeful hand skills.
Bahey, Noha G., Bailey, Mark E.S., Cobb, Stuart R., Edgar, Julia M., Gadalla, Kamal K.E., McGonigal, Rhona   +5 more
core   +1 more source

Protective effect of alirocumab, a PCSK9 inhibitor, on the sciatic nerve of rats with diabetic peripheral neuropathy

Endocrine Journal
Dyslipidemia has been considered a risk factor for diabetic peripheral neuropathy. Proprotein convertase subtilisin-like/Kexin 9 inhibitor (PCSK9) inhibitors are a new type of lipid-lowering drug currently in clinical use.
Na Cui, Yonghao Feng, Ming Wang, Xiuyan Lu, Yongmei Huang, Yinghui Chen, Xiaohong Shi   +6 more
openalex   +4 more sources

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration [PDF]

, 2015
Diabetic peripheral neuropathy affects up to half of diabetic patients. This neuronal damage leads to sensory disturbances, including allodynia and hyperalgesia.
Arimura, Barriere, Bates, Beazley-Long, Calcutt, Calcutt, Casanova-Molla, Chattopadhyay, Chen, Chen, Christianson, Costa, David O. Bates, Deguchi, Drake, Dunham, Duran-Jimenez, Eberhardt, Eisenstein, Ferrari, Galloway, Habib, Hamilton, Hamza Riaz, Hamzeh, Hargreaves, Hulse, Ibrahim, Kamiya, Kawamura, Koivisto, Kurt Ballmer Hofer, Lin, Lucy F. Donaldson, Materazzi, McNamara, Meseguer, Motawi, Murakami, Nicholas Beazley-Long, Nikita Ved, Nowak, Obrosova, Ohta, Oltean, Pawson, Price, Priya Singhal, Quattrini, Ragavendran, Rennel, Richard P. Hulse, Ropper, Russell, Samuel M. Bestall, Schratzberger, Simard, Simon-Yarza, Simovic, Sondell, Steve J. Harper, Tomlinson, Tomlinson, Tsantoulas, Verheyen, Wei, Woolard, Xu, Zochodne   +68 more
core   +2 more sources

The Effect of Co-administration of 4-Methylcatechol and Progesterone on Sciatic Nerve Function and Neurohistological Alterations in Streptozotocin-Induced Diabetic Neuropathy in Rats [PDF]

Cell Journal, 2011
Objective: Diabetic neuropathy is the most common complication of diabetes mellitusaffecting the nervous system. In this study, we investigated the in vivo effects of combinedadministration of 4-methylcatechol (4-MC) and progesterone (P) as a ...
Marzieh Panahi, Hamidreza Sameni
doaj  

CXCL12/CXCR4 axis: an emerging neuromodulator in pathological pain [PDF]

, 2016
The roles of chemokine C-X-C motif ligand 12 (CXCL12) and its receptor chemokine C-X-C motif receptor 4 (CXCR4) reveal this chemokine axis as an emerging neuromodulator in the nervous system. In the peripheral and central nervous systems, both CXCL12 and
Cheung, CW, Chung, SK, Luo, X, Wang, XMA, Xia, Z   +4 more
core   +1 more source

Prenatal alcohol exposure dysregulates spinal and circulating immune cell circular RNA expression in adult female rats with chronic sciatic neuropathy. [PDF]

Front Neurosci, 2023
Noor S, Pritha AN, Pasmay AA, Sanchez JE, Sanchez JJ, Fernandez-Oropeza AK, Sun MS, Dell'Orco M, Davies S, Savage DD, Mellios N, Milligan ED.   +11 more
europepmc   +1 more source

The Effect of Angipars on Diabetic Neuropathy in STZ-Induced Diabetic Male Rats: A Study on Behavioral, Electrophysiological, Sciatic Histological and Ultrastructural Indices [PDF]

, 2014
Nasser Zangiabadi, Hossein Mohtashami, Mahboobeh Hojatipour, Mandana Jafari, Majid Asadi‐Shekaari, Mohammad Shabani   +5 more
openalex   +1 more source