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Best Practice & Research Clinical Rheumatology, 2010
Sciatica is a symptom rather than a specific diagnosis. Available evidence from basic science and clinical research indicates that both inflammation and compression are important in order for the nerve root to be symptomatic. Tumour necrosis factor-alpha (TNF-alpha) is a key mediator in animal models, but its exact contribution in human radiculopathy ...
Valat, Jean-Pierre +4 more
openaire +4 more sources
Sciatica is a symptom rather than a specific diagnosis. Available evidence from basic science and clinical research indicates that both inflammation and compression are important in order for the nerve root to be symptomatic. Tumour necrosis factor-alpha (TNF-alpha) is a key mediator in animal models, but its exact contribution in human radiculopathy ...
Valat, Jean-Pierre +4 more
openaire +4 more sources
New England Journal of Medicine, 2017
This interactive feature on the management of sciatica offers a case vignette accompanied by essays that support recommending either lumbar disk surgery or nonsurgical treatment, including physical therapy.
Zoher Ghogawala +2 more
openaire +2 more sources
This interactive feature on the management of sciatica offers a case vignette accompanied by essays that support recommending either lumbar disk surgery or nonsurgical treatment, including physical therapy.
Zoher Ghogawala +2 more
openaire +2 more sources
Acta Orthopaedica Scandinavica, 1982
Investigation of the sagittal diameter of the spinal canal by ultrasound has shown a relative stenosis in patients with sciatica. In this study 12 patients who had recovered uneventfully after being operated on for herniated lumbar discs were found to have a broader spinal canal than 10 patients treated in the same way but still suffering from pain ...
Lillemor Forsberg, Anders Wallöe
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Investigation of the sagittal diameter of the spinal canal by ultrasound has shown a relative stenosis in patients with sciatica. In this study 12 patients who had recovered uneventfully after being operated on for herniated lumbar discs were found to have a broader spinal canal than 10 patients treated in the same way but still suffering from pain ...
Lillemor Forsberg, Anders Wallöe
openaire +3 more sources
Orthopedic Clinics of North America, 1991
The exact pathophysiologic mechanisms behind sciatica are incompletely known; however, compression of spinal nerve roots is known to be correlated to both pain and neural dysfunction in a segmental distribution of that specific nerve root. Compression per se may impair the transport of nutrients to the nerve tissue in such a way that affects the nerve ...
Björn Rydevik, Kjell Olmarker
openaire +3 more sources
The exact pathophysiologic mechanisms behind sciatica are incompletely known; however, compression of spinal nerve roots is known to be correlated to both pain and neural dysfunction in a segmental distribution of that specific nerve root. Compression per se may impair the transport of nutrients to the nerve tissue in such a way that affects the nerve ...
Björn Rydevik, Kjell Olmarker
openaire +3 more sources