Results 51 to 60 of about 50,911,861 (279)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Science-based climate targets for aviation fall short on mitigation and implementation

Environmental Research Letters
The Science-Based Targets initiative (SBTi) provides guidelines for setting company-level climate targets consistent with the Paris Agreement warming limit.
Joachim Peter Tilsted, Harald Buijtendijk, Eke Eijgelaar, Paul Peeters, Anders Bjørn   +4 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Almost 10 years of dual reporting of Scope 2: chaos or comparability?

Carbon Management
Investors, regulatory bodies, customers, and other stakeholders are increasingly concerned about climate change and demand meaningful, comparable and consistent corporate Greenhouse Gas (GHG) Emission Scope 1 and 2 data. Companies are responding to these
Sarah Stachelscheid, Andreas Dutzi
doaj   +1 more source

Design of Integration of Religion and Science in Handling Covid-19 Perspective of Ismail Raji Al Faruqi's Thought

Tribakti: Jurnal Pemikiran Keislaman, 2022
In the last two years, there has been a lot of discussion about the integration of religion and science. The discussion emerged as a response to the split in the logic of religious and scientific thinking regarding the handling of COVID-19. By conducting
Abd. Hannan
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

A framework for 1.5°C-aligned GHG budgets in architecture

Buildings & Cities
A methodological framework is presented for integrating 1.5°C-aligned greenhouse gas (GHG) budgets into architectural practice. Responding to the urgent need to decarbonise the built environment, this practice-oriented approach is based on the Carbon ...
Giovanni Betti, Ine Spaar, David Bachmann, Alexander Jerosch-Herold, Elena Kühner, Ruoxi Yang, Ketan Avhad, Stefan Sinning   +7 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Up to half of companies would be behind on their climate targets under stricter scope 2 accounting rules

Environmental Research Letters
Companies have been accused of overstating their scope 2 emission reductions through purchases of ineffective renewable energy certificates (RECs).
Anders Bjørn, Jens Friis Lund, Matthew Brander   +2 more
doaj   +1 more source