Science Learning, Science Teaching
, 2002 Esta publicación ofrece a los maestros una guía completa y crítica en la enseñanza y el aprendizaje de la ciencia. Combina una visión general de la investigación actual con los cambios del plan de estudios para proporcionar una guía práctica de la enseñanza en el aula.
Wellington, Jerry, Ireson, Gren
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Proceedings of the 42nd Annual Meeting of the Arizona-Nevada Academy of Science
, 1998 FORTY SECOND ANNUAL MEETING / April 18, 1998 / Glendale Community College / Glendale, Arizona / 1997-1998 Annual ReportsAbstracts from the annual meeting of the Arizona-Nevada Academy of Science.1998 Proceedings Supplement / Journal of the Arizona ...
Arizona-Nevada Academy of Science
core
The Electric and Magnetic Fields Instrument Suite and Integrated Science (EMFISIS): Science, Data, and Usage Best Practices. [PDF]
Space Sci Rev, 2023 Kletzing CA +9 more
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Proceedings of the 57th Annual Meeting of the Arizona-Nevada Academy of Science
, 2013 FIFTY SEVENTH ANNUAL MEETING / June 16-19, 2013 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / University of Nevada at Las Vegas / Las Vegas, NVAbstracts from the annual meeting of the Arizona ...
Arizona-Nevada Academy of Science
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Proceedings of the 41st Annual Meeting of the Arizona-Nevada Academy of Science
, 1997 FORTY FIRST ANNUAL MEETING / April 19, 1997 / The University of Nevada, Las Vegas / Las Vegas, NV / 1996-1997 Annual ReportsAbstracts from the annual meeting of the Arizona-Nevada Academy of Science.1997 Proceedings Supplement / Journal of the Arizona ...
Arizona-Nevada Academy of Science
core
Revisiting the Basic/Applied Science Distinction: The Significance of Urgent Science for Science Funding Policy. [PDF]
J Gen Philos Sci, 2022 Shaw J.
europepmc +1 more source