Science, technology, and innovation policy timing and nanotechnology entrepreneurship and innovation. [PDF]
PLoS One, 2022 Woolley JL, MacGregor N.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Harnessing science, technology, and innovation to drive synergy between climate goals and the SDGs. [PDF]
Innovation (Camb)Huang L +13 more
europepmc +1 more source
K-12 Science, Technology, Engineering, and Math characteristics and recommendations based on analyses of teaching cases in China. [PDF]
Front Psychol, 2022 Zheng Y +7 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Retracted: Optimization of Zero-Energy Buildings Based on Multicriteria Optimization Method
Adsorption Science & Technology, 2023 Adsorption Science and Technology
doaj +1 more source
Enhancing Lessons on the Internet of Things in Science, Technology, Engineering, and Medical Education with a Remote Lab. [PDF]
Sensors (Basel)Amador Nelke S +14 more
europepmc +1 more source
Are gender-science stereotypes barriers for women in science, technology, engineering, and mathematics? Exploring when, how, and to whom in an experimentally-controlled setting. [PDF]
Front Psychol, 2023 Sebastián-Tirado A +3 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source