Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Psychometric evidence of a science, technology, engineering, and mathematics career interest survey of Indonesian high school students. [PDF]
Sci RepAmalina IK, Vidákovich T, Thwe WP.
europepmc +1 more source
Science, technology, and innovation policy timing and nanotechnology entrepreneurship and innovation. [PDF]
PLoS One, 2022 Woolley JL, MacGregor N.
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Retracted: Intelligent Forecasting of Air Quality and Pollution Prediction Using Machine Learning
Adsorption Science & Technology, 2023 Adsorption Science and Technology
doaj +1 more source
Harnessing science, technology, and innovation to drive synergy between climate goals and the SDGs. [PDF]
Innovation (Camb)Huang L +13 more
europepmc +1 more source
Impacts of the COVID-19 pandemic on scientists' productivity in science, technology, engineering, mathematics (STEM), and medicine fields. [PDF]
Humanit Soc Sci Commun, 2022 Heo S +5 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source