Results 21 to 30 of about 8,608,838 (358)
, 1994 A draft fish survey report on comprehensive analysis for water rights claims in the Upper Klamath River Basin, Oregon from July ...
EA Engineering, Science, and Technology
core +4 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
, 1994 A draft fish survey report on comprehensive analysis for water rights claims in the Upper Klamath River Basin, Oregon from July ...
EA Engineering, Science, and Technology
core +4 more sources
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
FEBS Letters, EarlyView.Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka +6 more
wiley +1 more source
FEBS Letters, EarlyView.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source
Entity Alignment Method of Science and Technology Patent based on Graph Convolution Network and Information Fusion [PDF]
arXiv, 2023 The entity alignment of science and technology patents aims to link the equivalent entities in the knowledge graph of different science and technology patent data sources. Most entity alignment methods only use graph neural network to obtain the embedding of graph structure or use attribute text description to obtain semantic representation, ignoring ...
arxiv
The Philippine journal of science. [PDF]
, 1918 v.20 ...
Industrial Technology Development Institute (Philippines) +12 more
core +3 more sources
FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source
Knowledge for a warmer world: a patent analysis of climate change adaptation technologies [PDF]
arXiv, 2021 Technologies can help strengthen the resilience of our economy against existential climate-risks. We investigate climate change adaptation technologies (CCATs) in US patents to understand (1) historical patterns and drivers of innovation; (2) scientific and technological requirements to develop and use CCATs; and (3) CCATs' potential technological ...
arxiv