Results 51 to 60 of about 18,472,577 (406)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Graphite in Science and Nuclear Technology [PDF]

open access: yesarXiv, 2015
This review is devoted to the application of graphite and graphite composites in the science and technology. Structure and electrical properties, technological aspects of producing of high-strength artificial graphite and dynamics of its destruction are considered.
arxiv  

Scientific Illiteracy: Causes, Costs and Cures [PDF]

open access: yes, 1989
[Excerpt] This article examines the causes of the learning deficits in science, math and technology, evaluates their social costs and then recommends policy measures for remedying the problems identified.
Bishop, John H.
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Integration of Media Design Processes in Science, Technology, Engineering, and Mathematics (STEM) Education.

open access: yes, 2015
Problem Statement :Science, technology, engineering and mathematics (STEM) education aims at improving students’ knowledge and skills in science and math, and thus their attitudes and career choices intheseareas. The ultimate goal in STEM education is to
E. Karahan   +2 more
semanticscholar   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Evaluation of a Teaching Sequence Regarding Science, Technology and Society Values in Higher Education

open access: yes, 2015
This work shows the results of a teaching-learning sequence applied to the concept of the nature of science and technology implemented on manufacturing technology engineering students at Autonomous University of Baja California, Mexico, during the ...
M. Oliveros   +2 more
semanticscholar   +1 more source

Science, Technology and U.S. Economic Policy [PDF]

open access: yes, 1986
Volume 3 - Paper #44_44ScienceTechnologyandUSeconomical.pdf: 194 downloads, before Oct.
Briggs, Vernon M., Jr.
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Exploring the tension and synergies between science and technology in science education [PDF]

open access: yes, 2009
This chapter explores the way in which technology has been introduced through and by science educators in Australasia in the last 25 years. A number of themes have arisen in this time from using technology to engage students in science, exploring the ...
Jones, Alister
core  

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