Results 51 to 60 of about 8,608,838 (358)

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Testing the science/technology relationship by analysis of patent citations of scientific papers after decomposition of both science and technology [PDF]

open access: yesarXiv, 2017
The relationship of scientific knowledge development to technological development is widely recognized as one of the most important and complex aspects of technological evolution. This paper adds to our understanding of the relationship through use of a more rigorous structure for differentiating among technologies based upon technological domains ...
arxiv  

The Rollamo 2010 [PDF]

open access: yes, 2010
https://scholarsmine.mst.edu/speccoll_yearbooks/1106/thumbnail ...
Missouri University of Science and Technology
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Science and technology in Mexico [PDF]

open access: yesNature Materials, 2010
Mexico's economy is doing relatively well, but its science is chronically under-supported and the country's technological dependence is increasing rapidly. Without a strong science and technology base, the nation's future is at risk.
openaire   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Common Ground Newsletter Fall 2020 [PDF]

open access: yes, 2020
-Summer internships amid COVID-19-Class of 2020 recognition and celebration -Kummer Design Center expansionhttps://scholarsmine.mst.edu/common-ground/1008/thumbnail ...
Missouri University of Science and Technology
core   +3 more sources

The Bridge Newsletter Spring 2022 [PDF]

open access: yes, 2022
-CArEE faculty awarded Kummer Ignition Grants -Geldert-Murphey poised to become ASCE’s 2023 president-elect -Nine new members inducted during Academy of Civil Engineers 50th anniversary celebration -Steel Bridge Team wins fourth consecutive regional ...
Missouri University of Science and Technology
core   +1 more source

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