Results 71 to 80 of about 136,634 (221)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Improved thermal stability of TbF3-coated sintered Nd-Fe-B magnets by electrophoretic deposition

, 2018
Rotary ultrasonic milling; quartz glass; surface roughness; surface ...
Guo, S., Ding, G. F., Chen, L., Di, J. H., Cao, X. J., Chen, K. Z., Yan, A. R., Chen, R. J.   +7 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Development of Southeast Asia Regional Standards for Science Teachers: Implication for Equitable Outcome in Science and Technology Education

, 2017
In any world-class educational system, quality teachers with passion for Continuing Professional Development (CPD) play important roles in the nation’s human resource development especially in the fields of Science and Technology Education (STE).  ...
Science and Technology Education for a P, XVII IOSTE SYMPOSIUM
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

IEEE Transactions on Emerging Topics in Computing

IEEE Transactions on Emerging Topics in Computing publishes papers on emerging aspects of computer science, computing technology, and computing applications not currently covered by other IEEE Computer Society ...
Metra, C.
core  

Electrically conductive bacterial nanowires produced by Shewanella oneidensis strain MR-1 and other microorganisms

, 2006
Shewanella oneidensis MR-1 produced electrically conductive pilus-like appendages called bacterial nanowires in direct response to electron-acceptor limitation.
Watanabe, Kazuya, Ishii, Shun'ichi, McLean, Jeffrey S., Kim, Byung Hong, Dohnalkova, Alice, CHANG, IN SEOP, Logan, Bruce, Beveridge, Terry J., Saffarini, Daad A., Gorby, Yuri A., Moyles, Dianne, Culley, David E., Kennedy, David W., Pinchuk, Grigoriy, Romine, Margaret F., Fredrickson, Jim K., Nealson, Kenneth H., Rosso, Kevin M., Shi, Liang, Reed, Samantha B., Kim, Kyung Shik, Hill, Eric A., Elias, Dwayne A., Yanina, Svetlana   +23 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Computer science as an integrated part of engineering education

, 1998
The Information Technology curriculum at Linköping University has as goal to form engineers with an integrated view of engineering. The teaching philosophy in this curriculum is Problem-Based Learning.
Kamkar, Mariam,, Mariam Kamkar, Lambrix, Patrick,, Patrick Lambrix   +3 more
core   +1 more source