Results 191 to 200 of about 1,513,570 (265)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Application of gas chromatography-mass spectrometry-based metabolomics in food science and technology.

Journal of Bioscience and Bioengineering, 2022
Metabolomics is a tool used for quantitative assessment of metabolites that has been applied extensively in the field of food science. Recently, metabolomics-based gas chromatography-mass spectrometry (GC/MS) is becoming a common tool for analyzing, not ...
S. Putri   +6 more
semanticscholar   +1 more source

TENDL: Complete Nuclear Data Library for Innovative Nuclear Science and Technology

Nuclear Data Sheets, 2019
The TENDL library is now established as one of the major nuclear data libraries in the world, striving for completeness and quality of nuclear data files for all isotopes, evaluation methods, processing and applied performance. To reach this status, some
A. Koning   +7 more
semanticscholar   +1 more source

Attosecond Technology and Science

IEEE Journal of Selected Topics in Quantum Electronics, 2012
The generation of attosecond pulses has been the result of tremendous efforts and advances in the field of the interaction of ultrashort intense laser pulses with matter. Nowadays, the electric field waveform of femtosecond pulses can be precisely controlled and used to synthesize and measure the evolution in time of attosecond pulses.
SANSONE, GIUSEPPE   +2 more
openaire   +3 more sources

The cognitive science of technology

Trends in Cognitive Sciences, 2021
Technology is central to human life but hard to define and study. This review synthesizes advances in fields from anthropology to evolutionary biology and neuroscience to propose an interdisciplinary cognitive science of technology. The foundation of this effort is an evolutionarily motivated definition of technology that highlights three key features:
openaire   +2 more sources

Science and technology roadmaps

IEEE Transactions on Engineering Management, 2001
Science and technology (ST ST enhancing communications among researchers, technologists, product managers, suppliers, users, and other stakeholders; identifying gaps and opportunities in ST and identifying obstacles to rapid and low-cost product development.
Ronald N. Kostoff, Robert R. Schaller
openaire   +1 more source

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