Results 121 to 130 of about 199,533 (304)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Medical image segmentation network based on multi-scale cross-attention and wavelet transform

Journal of King Saud University: Computer and Information Sciences
Medical image segmentation is a key technology for computer-aided diagnosis and treatment planning, essential for early disease detection, precise diagnosis, and prognosis evaluation.
Fan Qin, Yongjie Liang, Chaofeng Yang, Yulong Cao, Jiaying Fan, Peiyuan Wang, Bizhong Wei   +6 more
doaj   +1 more source

AI-infused Security: Robust Defense by Bridging Theory and Practice [PDF]

, 2019
Presented on April 5, 2019 at 12:00 p.m. in the Klaus Advanced Computing Building, Room 1116.Shang-Tse Chen is a Ph.D. Candidate in Computer Science at Georgia Tech. He works in the intersection of applied and theoretical machine learning.
Chen, Shang-Tse
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Quantum classical hybrid convolutional neural networks for breast cancer diagnosis

Scientific Reports
The World Health Organization states that early diagnosis is essential to increasing the cure rate for breast cancer, which poses a danger to women’s health worldwide.
Qiuyu Xiang, Dongfen Li, Zhikang Hu, Yuhang Yuan, Yuchen Sun, Yonghao Zhu, You Fu, Yangyang Jiang, Xiaoyu Hua   +8 more
doaj   +1 more source

Practical and Analyst-Acceptable Explainable AI for Supporting Decision-Making in SOCs

IEEE Access
In the evolving cybersecurity landscape, Security Operation Centers (SOCs) play a pivotal role in protecting digital assets through real-time threat detection and response. Recently, the integration of Artificial Intelligence (AI) and Explainable AI (XAI)
Hyunwoo Lee, Ui-Jun Baek, Taewoong Kwon, Jun Lee, Jungsuk Song   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

PIA-A secure and efficient identity authentication scheme in telemedicine via the PUF method

Scientific Reports
With the rise of IoT technology, remote medical services have gained increasing attention. These services became particularly popular during the COVID-19 pandemic due to their convenience, privacy, and ability to transcend geographical boundaries.
Xiong Wang, Wenbo Wang, Ang Liu, Wen Liu, Zehao Zhang, Weilin Li   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source