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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The Handbook of Science and Technology Studies</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Análise Social</i>, 2010 </span><br><span class="r_sub"><i>Ana Delicado</i></span><br><small><a href="https://doaj.org/article/7e1042bbb19f4455895a9e6b68d71bfc" target="_blank" rel="nofollow" title="doaj.org/article/7e1042bbb19f4455895a9e6b68d71bfc">doaj</a> </small>   <br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1186/s40359-025-03881-9" target="_blank" rel="nofollow">The relationship between HIV infection and depression and their determinants in the MSM population in Eastern China: an analysis based on decision tree modelling and logistic regression.</a> <b><a href="https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC12866518&blobtype=pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>BMC Psychol</i></span><br><span class="r_sub"><i>Zhou Y<span id="ma_5" style="display:none">, Zhang Z, Li W, Zeng L, Shan C, Chen T, Zhou ZM.</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_5')">+6 more</a></small></i></span><br><small><a href="https://europepmc.org/article/MED/41484908#free-full-text" target="_blank" rel="nofollow" title="europepmc.org/article/MED/41484908#free-full-text">europepmc</a> </small>   <div id="more_5" style="display:none"><a href="/sci_redir.php?doi=10.1186%2Fs40359-025-03881-9" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1186/s40359-025-03881-9'); alert('Copied the doi');">copy doi</a> <small>(10.1186/s40359-025-03881-9)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_5')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70192" target="_blank" rel="nofollow">Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.</span><br><span class="r_sub"><i>Hanne Goris<span id="ma_6" style="display:none">, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_6')">+10 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70192?mi=2or9o2m&af=R&AllField=science and technology studies&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70192?mi=2or9o2m&af=R&AllField=science and technology studies&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_6" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70192" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70192'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70192)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_6')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.3390/toxics14010107" target="_blank" rel="nofollow">Pyrrhotite Facilitates Growth and Cr Accumulation in <i>Leersia hexandra</i> Swartz for Effective Cr(VI) Removal in Constructed Wetlands.</a> <b><a href="https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC12845952&blobtype=pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Toxics</i></span><br><span class="r_sub"><i>Zhang X<span id="ma_7" style="display:none">, Zhang X, Lin Y, Lv J, Jiang M, Cheng S, Yan J.</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_7')">+6 more</a></small></i></span><br><small><a href="https://europepmc.org/article/MED/41600656#free-full-text" target="_blank" rel="nofollow" title="europepmc.org/article/MED/41600656#free-full-text">europepmc</a> </small>   <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.3390%2Ftoxics14010107" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.3390/toxics14010107'); alert('Copied the doi');">copy doi</a> <small>(10.3390/toxics14010107)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70193" target="_blank" rel="nofollow">Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.</span><br><span class="r_sub"><i>Carolin Salmon<span id="ma_8" style="display:none">, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+9 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70193?mi=2or9o2m&af=R&AllField=science and technology studies&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70193?mi=2or9o2m&af=R&AllField=science and technology studies&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70193" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70193'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70193)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.7759/cureus.100052" target="_blank" rel="nofollow">A Student-Led Mentorship Intervention to Enhance Podoconiosis Management Among Healthcare Workers and Village Health Teams in Western Uganda.</a> <b><a href="https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC12831194&blobtype=pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Cureus</i></span><br><span class="r_sub"><i>Mwesigye V<span id="ma_9" style="display:none">, Tebulwa JB, Ngabirano J, Muhwezi TJ, Ngasha R, Najjingo DP, Lubwama H, Kawungezi PC, Kitunzi Mulyowa G, Mulogo E.</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+9 more</a></small></i></span><br><small><a href="https://europepmc.org/article/MED/41583242#free-full-text" target="_blank" rel="nofollow" title="europepmc.org/article/MED/41583242#free-full-text">europepmc</a> </small>   <div id="more_9" style="display:none"><a href="/sci_redir.php?doi=10.7759%2Fcureus.100052" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.7759/cureus.100052'); alert('Copied the doi');">copy doi</a> <small>(10.7759/cureus.100052)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://openalex.org/W2971226106" target="_blank" rel="nofollow">A study of vegetative and reproductive development in Caucasian clover (Trifolium ambiguum, M. Bieb.) cv. Monaro : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Seed Technology at Massey University, Palmerston North, New Zealand</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: gold" title="open access: gold" width="16" height="16">, 1993 </span><br><span class="r_sub"><i>Faham Efendi</i></span><br><small><a href="https://openalex.org/W2971226106" target="_blank" rel="nofollow" title="openalex.org/W2971226106">openalex</a> </small>   <div id="more_10" style="display:none"><a href="http://hdl.handle.net/10179/14924" target="_blank" rel="nofollow" title="hdl.handle.net/10179/14924">hdl.handle.net</a><br> </div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-computer_science/" class="suggestion"onclick="show_loader();"><b>computer science</b></a><br/><a href="/q-engineering/" class="suggestion"onclick="show_loader();"><b>engineering</b></a><br/><a href="/q-political_science/" class="suggestion"onclick="show_loader();"><b>political science</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-psychology/" class="suggestion"onclick="show_loader();"><b>psychology</b></a><br/><a href="/q-sociology/" class="suggestion"onclick="show_loader();"><b>sociology</b></a><br/><a href="/q-medicine/" class="suggestion"onclick="show_loader();"><b>medicine</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-philosophy/" class="suggestion"onclick="show_loader();"><b>philosophy</b></a><br/><a href="/q-engineering_ethics/" class="suggestion"onclick="show_loader();"><b>engineering ethics</b></a><br/><a href="/q-business/" class="suggestion"onclick="show_loader();"><b>business</b></a><br/></div></div></div><div class="pagenav"><a href="/q-science_and_technology_studies/p-23/" rel="nofollow"><b>previous</b></a>   <a href="/q-science_and_technology_studies/p-22/" rel="nofollow">22</a>  <a href="/q-science_and_technology_studies/p-23/" rel="nofollow">23</a>  <b>24</b>  <a href="/q-science_and_technology_studies/p-25/" rel="nofollow">25</a>  <a href="/q-science_and_technology_studies/p-26/" rel="nofollow">26</a>   <a href="/q-science_and_technology_studies/p-25/" id="next" rel="nofollow"><b>next</b></a> </div><br></div> </div> <script>document.getElementById('loadingGif').style.display='none';</script><div style="width: 100%; height: 40px; bottom: 0px; background-color: #f5f5f5;"><div style="padding-left: 15px; padding-top: 10px"> <a href="/" rel="nofollow">Home</a> - <a href="/page-about/" rel="nofollow">About</a> - <a href="/page-disclaimer/" rel="nofollow">Disclaimer</a> - <a href="/page-privacy/" rel="nofollow">Privacy</a> </div></div> <link rel="stylesheet" href="//ajax.googleapis.com/ajax/libs/jqueryui/1.11.4/themes/smoothness/jquery-ui.min.css"/> </body> </html>