Results 51 to 60 of about 22,602 (253)
This paper looks at ways to think about the relationship between the knowledge that we produce and its social origins without falling into a naïve determinism.
Geoffrey C. Bowker
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Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng +17 more
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Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su +7 more
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A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li +15 more
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A Fragile Field. The Development and Transformation of Science and Technology Studies in Switzerland
This contribution reconstructs the history of Science and Technology Studies in Switzerland. With a focus on the institutional aspects of the field’s emergence, it traces early initiatives to foster social research on science and technology, then ...
Regula Valérie Burri, Martina Merz
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Phase separation emerges during the initial growth of heavily Ni‐ and Ni,Nb‐co‐doped STO thin films, leading to preferential accumulation of Ni and embedded NiOx nanoinclusions in thicker films. Nb co‐doping partially suppresses the ordering of these embedded structures, comprising about 20% of all Ni ions.
Yen‐Po Liu +7 more
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Now commonly adopted as the point of reference for musicians in the Western world, A 440hz only became the standard pitch during an international conference held in London in 1939.
Fanny Gribenski
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Solvent‐processable polyoxovanadate–PMMA nanocomposites exhibit concentration‐dependent 2D and 3D organization on gold surfaces, while retaining multilevel redox switching at room temperature. These hybrids bridge nanoscale functionality and macroscopic measurement, establishing a versatile platform for hybrid molecular–polymer memory materials ...
Jonas Lorenz +11 more
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The relation between STS and the social sciences is far from simple. While including STS in the field of social sciences is an object of dispute for certain researchers, others have tried to involve, seduce, or debate with colleagues in other subfields ...
Pablo Kreimer
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Advancing Energy Materials by In Situ Atomic Scale Methods
Progress in in situ atomic scale methods leads to an improved understanding of new and advanced energy materials, where a local understanding of complex, inhomogeneous systems or interfaces down to the atomic scale and quantum level is required. Topics from photovoltaics, dissipation losses, phase transitions, and chemical energy conversion are ...
Christian Jooss +21 more
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