Results 91 to 100 of about 32,527,195 (312)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Anti-science and the science community

Nature Reviews Microbiology
As anti-science sentiment intensifies — aggravated by the pandemic, driven in some parts of the world by political actors and amplified by social media — the scientific community finds itself under increasing scrutiny, and in some cases, even direct attack.
openaire   +2 more sources

Science policy, science funding, and the science community

Academic Medicine, 1991
The ongoing federal budget crisis has led to extensive debate over how much money the federal government should spend on scientific research. In the struggle for limited funds, many advocacy groups will covet the large sums proposed for science research, and the scientific community may be called upon to justify its large share of the discretionary ...
openaire   +3 more sources

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The Science Communication Challenge

, 2018
The Science Communication Challenge explores and discusses the whys – as distinct from the hows – of science communication. Arguing that the dominant science communication paradigm is didactic, it makes the case for a political category of science ...
Meyer, Gitte
core  

Third-Person Perception of Science Narratives: The Case of Climate Change Denial

, 2018
Science communicators are increasingly recognizing the potential of narratives to reach and influence audiences. However, do audiences recognize and consider this tactic when evaluating how such messages influence themselves and others?
Rosenthal, Sonny, Dahlstrom, Michael Field, Sonny Rosenthal, Michael Field Dahlstrom   +3 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

The Credibility of Science Communication

Communicating Astronomy with the Public Journal, 2007
Current developments in the media marketplace and an increased need for visibility to secure funding are leading inevitably to faster, simpler and more aggressive science communication.
Nielsen, L. H., Jørgensen, N. T., Jantzen, K., Christensen, L. L.   +3 more
doaj  

Can Strategic and Democratic Goals Coexist in Communicating Science? Nanotechnology as a Case Study in the Ethics of Science Communication and the Need for “Critical” Science Literacy [PDF]

, 2013
Science communication emerges from social contexts in which the value of popular support for science and technology (S&T) is presumed. This article does not dispute the assertion that S&T is “good” but does assume that people should make free and ...
Susanna Priest, Priest, Susanna
core   +1 more source