Results 131 to 140 of about 11,711,564 (342)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Systems of innovation are systems of mediation: a discussion of the critical role of science communication in innovation and knowledge-based development [PDF]

open access: yes, 2000
This discussion paper highlights the critical role of science communication, not as an 'add-on' topic to bring about the acceptance of science, but as a process which guides the processes of innovation and knowledge-based development.
Gristock, Jenny
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Conceptual Model for Communication [PDF]

open access: yes, 2009
A variety of idealized models of communication systems exist, and all may have something in common. Starting with Shannons communication model and ending with the OSI model, this paper presents progressively more advanced forms of modeling of ...
Alsaqa, Alaa   +2 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Internal networks revisited: Telepathy meets technology [PDF]

open access: yes, 2003
This conference paper is available to download from the publisher’s website at the link below.This is speculative paper that explores the paradigm-shifting concept of initiating a mind/body to computer communication or interaction, it is not intended ...
Baker, C
core  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

The Credibility of Science Communication

open access: yesCommunicating Astronomy with the Public Journal, 2007
Current developments in the media marketplace and an increased need for visibility to secure funding are leading inevitably to faster, simpler and more aggressive science communication.
Nielsen, L. H.   +3 more
doaj  

Connecting Research with Communities through Performative Social Science [PDF]

open access: yes, 2012
A pioneer in Performative Social Science, Kip Jones makes a case for the potential of arts-based social science to reach audiences and engage communities.
Jones, Kip
core   +1 more source

Complexity science and intentional systems

open access: yes, 2008
In their position paper entitled "Towards a new, complexity science of learning and education", Jorg et al. (2007) argue that educational research is in crisis.
Leydesdorff, Loet
core   +2 more sources

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