Results 131 to 140 of about 4,501,989 (341)
Beyond the "common context" : the production and reading of the Bridgewater Treatises [PDF]
The Bridgewater Treatises were among the most widely circulated books of science in early nineteenth-century Britain, yet little is known of their contemporary readership.
Topham, J.R.
core
The role of lipid metabolism in neuronal senescence
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Teaching science students to communicate - a teaching resource [PDF]
This teaching resource contains five science communication activities, to be run in undergraduate science classes such as workshops, practicals, or tutorials.
Kuchel, Louise, Mercer-Mapstone, Lucy
core
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
How are science teachers using their TELA laptop? [PDF]
The Digital Horizons: Laptops for teachers scheme provides teachers whose schools opt into the TELA scheme access to a laptop for their exclusive use. This paper reports on a three-year evaluation of the impact of the TELA laptops on teachers’ work.
Cowie, Bronwen +2 more
core +1 more source
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source

