Results 111 to 120 of about 36,599,232 (307)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
School transport for children with special needs
, 1999 Department of Education and Science / [200?
Department of Education and Science
core
Modeling competence in science education
Disciplinary and Interdisciplinary Science Education Research, 2019 Research on the understanding of the nature of models and modeling processes in science education have received a lot of attention in science education.
Mei-Hung Chiu, Jing-Wen Lin
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Personal Health—Personalized Science: A new driver for science education?
, 2014 Since the 1950s, originating with and driven by the Sputnik shock, there have been tremendous efforts to improve science education. Over the past two decades, the initial focus on science content has been abandoned, at least among many science education ...
Roth, Michael
core +1 more source
Mongolian Education and Science Vocabulary
Oriental StudiesIntroduction. The article deals with semantics and etymology of several basic terms of Mongolian culture vocabulary relating to education and science. Goals.
Anna V. Mazarchuk
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Education Extended : A Sociomaterialist Perspective on Science Education
, 2018 This essay uses a sociomaterialist perspective to shed new light on science education in general and scientific inquiry in particular. The focus is on human and non-human actors in science education—the pupil and the microscope.
Jobér, Anna
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Defining integrated science education and putting it to test
, 2008 The thesis is made up by four studies, on the comprehensive theme of integrated and subject-specific science education in Swedish compulsory school. A literature study on the matter is followed by an expert survey, then a case study and ending with two ...
Åström, Maria
core +2 more sources