Results 111 to 120 of about 50,459 (259)

Very First Application of Compact Benchtop NMR Spectrometers to Complex Biofluid Analysis and Metabolite Tracking for Future Metabolomics Studies: A Retrospective Decennial Report from November 2014

Applied Sciences
Herein we report the very first experiments which were conducted in an attempt to demonstrate the ability of low-field (LF), compact benchtop NMR spectrometers to provide spectral profiles of whole human biofluids, which took place in September–November ...
Martin Grootveld, Victor Ruiz-Rodado, Anna Gerdova, Mark Edgar   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Sex and age differences in the association between heart rate variability and cardiac chronotropy: A replication‐extension study

Physiological Reports
Using heart rate variability (vmHRV) as a proxy of cardiac vagal modulation, previous studies have hinted at sex differences in the vagal control of cardiac chronotropy in young adults, but little is known in older individuals. The current study aimed at
Luca Carnevali, Darcianne K. Watanabe, Margherita Barbetti, Suzi Hong, DeWayne P. Williams, Jordan Kohn, Julian Koenig, Julian F. Thayer   +7 more
doaj   +1 more source

“We’re not just patients”: A qualitative examination of public safety service users’ experiences with staff at an inpatient mental health treatment facility in Canada

Journal of Community Safety and Well-Being
Posttraumatic stress disorder and substance use disorder (SUD) are highly prevalent among public safety professionals (PSP), including first responders and active/retired military members, due to the trauma-laden nature of their work and associated ...
Krystle Martin, Emma Vester, Rosemary Ricciardelli, Matthew S. Johnston, Shawn Carter   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Sense of Belonging, DFW Reduction, and Student Success: Centering Student Experience in Groups with Ethnographic Methods

Education Sciences
Despite substantial instructional attention to large-enrollment university courses in science, technology, engineering, and mathematics (STEM), they tend to have high rates of D, F, and Withdraw (DFW) at the introductory level that disproportionally ...
Jennifer Meta Robinson, Rachel Seymour, Seonmi Jin, Rodney S. Whiteman   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Introduction to Science Gateways and Science Gateway Frameworks [PDF]

, 2014
openaire   +3 more sources

A catalog of API Gateway metrics and its quantitative evaluation

Dyna
In the rapidly evolving API Economy, quality of API management software has become a critical concern. This work analyzed the API management industry with a particular focus on the metrics available for various API Gateway products.
Eder dos Santos, Sandra Casas
doaj   +1 more source

Is Forensic Science a Gateway for Women in Science?

Forensic Science Policy & Management: An International Journal, 2009
Abstract Encouraging women to pursue science, technology, engineering, and mathematics (STEM) careers is an important part of a skilled, diverse workforce. While women constitute nearly half of the U.S. workforce, they make up only one-third to one-fifth of the nation's STEM careers. The lack of women in science is a “hallmark characteristic of science
openaire   +1 more source