Results 221 to 230 of about 21,296,625 (392)
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Serum HMGB1 levels in elderly patients undergoing general anesthesia with dexmedetomidine and its correlation with early postoperative cognitive dysfunction. [PDF]
Zhou H +5 more
europepmc +1 more source
The Structural-Genetic Theory Programme as General Theory to Social Sciences [PDF]
Georg W. Oesterdiekhoff
openalex +1 more source
Scientific session of the General meeting of the Physical Sciences Division of the Russian Academy of Sciences (7 December 2015) [PDF]
openalex +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Analyzing the role of science practices in general chemistry courses and assessments
Jessica J. Reed
openalex +2 more sources
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Erratum: Kang Ru enhances paclitaxel's efficacy against breast cancer progression. [PDF]
Chang CM +9 more
europepmc +1 more source

