Results 141 to 150 of about 2,541,008 (299)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Research Journey of Advances in Human Biology: Visualisation Approach

open access: yesAdvances in Human Biology
This paper conducts the bibliometric analysis of 525 articles published in the journal ‘Advances in Human Biology’ from 2013 to 2024. The data were sourced from the Web of Science database. The study focuses on various aspects of the journals such as the
Vasantray Chauhan   +2 more
doaj   +1 more source

Construction and Demolition Waste Management Research: A Science Mapping Analysis. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Elshaboury N   +3 more
europepmc   +1 more source

Definition of Atmospheric Science Experiments and Techniques: Wake Zone Mapping Experiments [PDF]

open access: yes
The development of a subsatellite system has been proposed for the shuttle program which would provide to the scientific community a platform for experiments which would be tethered to the shuttle spacecraft orbiting at about 200 km altitude. Experiments
Taeusch, D. R.
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

City brand evolution research and future agenda: bibliometric and science mapping analysis. [PDF]

open access: yesHeliyon, 2022
Duque Oliva EJ   +2 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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