Results 141 to 150 of about 2,545,043 (343)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Community engagement to tackle infectious threats: A viewpoint based on a social science mapping process in Bangladesh, Uganda, and Ukraine. [PDF]

open access: yesJ Glob Health, 2023
Jirovsky-Platter E   +10 more
europepmc   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Green Human Resource Management in the manufacturing sector: a bibliometric literature review

open access: yesEngineering Management in Production and Services
This study aims to examine the structure of Green Human Resource Management (GHRM) within the manufacturing industry research field and identify future research directions in this area as GHRM increasingly gains scholarly attention. This study utilised a
Austen Agata, Piwowar-Sulej Katarzyna
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Bridging behavior science and gaming theory: Using the Intervention Mapping Protocol to design a serious game against cyberbullying

open access: green, 2015
Ann DeSmet   +10 more
openalex   +2 more sources

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