Results 121 to 130 of about 4,197,929 (308)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Awareness, Use, and Value of Student Support Programs Through the Lens of Science Students, Professors, and Staff

Canadian Journal for the Scholarship of Teaching and Learning
Science students face specific challenges associated with their field of study. The purpose of this study was to assess science students’ use of support services and programs, identify barriers to use and group differences, determine professors’ and ...
A. Dana Ménard, Sira Jaffri, Kendall Soucie, Dora Cavallo-Medved, Chris Houser   +4 more
doaj   +1 more source

A proposal for measuring the benefits of policy-oriented social science research: [PDF]

This paper addresses the problem of how to measure the benefits of policy-oriented social science research. It argues that social science research promotes economic efficiency in three different ways—it fosters efficiency in the public sector both ...
Park, Donghyun
core  

Uncertainty in climate science and climate policy [PDF]

, 2014
This essay, written by a statistician and a climate scientist, describes our view of the gap that exists between current practice in mainstream climate science, and the practical needs of policymakers charged with exploring possible interventions in the ...
Crucifix, Michel, Rougier, Jonathan
core   +1 more source

Coexisting Rashba/Dresselhaus Spin Splitting in Solution‐Processed Bournonite Films Using Circular Photogalvanic Effect

Advanced Functional Materials, EarlyView.
Circular photogalvanic effect measurements and first‐principles calculations reveal spin‐splitting states in solution‐processed bournonite films (CuPbSbS3) due to structural and bulk inversion asymmetry. The results provide experimental confirmation of coexisting Rashba and Dresselhaus spin‐splitting states in this non‐centrosymmetric chalcogenide ...
Aeron McConnell, Sasa Wang, Andrew Grieder, Yuan Ping, David B. Mitzi, Dali Sun   +5 more
wiley   +1 more source

Towards an inclusive Open Science: examining EDI and public participation in policy documents across Europe and the Americas

Royal Society Open Science
National, international and organizational Open Science (OS) policies are being formulated to improve and accelerate research through increased transparency, collaboration and better access to scientific knowledge.
Natascha Chtena, Juan Pablo Alperin, Esteban Morales, Alice Fleerackers, Isabelle Dorsch, Stephen Pinfield, Marc-André Simard   +6 more
doaj   +1 more source

Entrepreneurial Experiments in Science Policy: Analizing the Human Genome Project [PDF]

We re-conceptualize the role of science policy makers, envisioning and illustrating their move from being simple investors in scientific projects to entrepreneurs who create the conditions for entrepreneurial experiments and initiate them.
Fiona E. Murray, Kenneth G. Huang
core  

Analysis of Climate Policy Targets under Uncertainty [PDF]

, 2009
and PDF report are also available on the MIT Joint Program on the Science and Policy of Global Change website (http://globalchange.mit.edu/).Although policymaking in response to the climate change is essentially a challenge of risk management, most ...
Forest, Chris Eliot, Jacoby, Henry D., Kicklighter, David W., Melillo, Jerry M., Paltsev, Sergey, Prinn, Ronald G., Reilly, John M., Sarofim, Marcus C., Schlosser, C. Adam, Sokolov, Andrei P., Wang, Chien, Webster, Mort D.   +11 more
core   +1 more source

Selective Separation of the Rare Earth Elements Dysprosium and Neodymium via Tailoring Nanocellulose Chemical Structure

Advanced Functional Materials, EarlyView.
Dicarboxylate‐modified anionic hairy cellulose nanocrystals exhibit a high selectivity for dysprosium(III) over neodymium(III). This selectivity arises from disordered dicarboxylate cellulose “hairs” that enable cooperative ionic coordination, hydrogen bonding, and strain‐induced conformational shrinkage.
Roya Koshani, Shang‐Lin Yeh, Karuna Anna Sajeevan, Mica L. Pitcher, Dawson Alexander, Ratul Chowdhury, Amir Sheikhi   +6 more
wiley   +1 more source