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Advanced Science, EarlyView.Machine learning models predict in real time the onset of harmful microbubble collapse during microbubble‐enhanced focused ultrasound (MB‐FUS) and enable dynamic adjustment of sonication to prevent cavitation‐induced damage. This predictive control expands the safe operating window for bloodbrain barrier opening, enhancing nanoparticle delivery and ...
Hohyun Lee +17 more
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Advanced Science, EarlyView.Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao +16 more
wiley +1 more source
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Science Policy and Science Policy Research
Nature, 1970This assessment of the value of science policy research in the making of policies is based on a lecture given at a meeting of the Sociology of Science Study Group of the British Sociological Association last March. The thoughts it contains are of course those of Dr Blume himself, and not of the Department of Education and Science or the Council for ...
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Science, 1982
Industry is now investing heavily and at an increasing rate in research and development. The government's responsibility should be to assure that this industrial spending is paralleled by real growth in its support of basic research. Such growth is realistic, even in times of budgetary constraints, given a proposed compact between the scientific ...
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Industry is now investing heavily and at an increasing rate in research and development. The government's responsibility should be to assure that this industrial spending is paralleled by real growth in its support of basic research. Such growth is realistic, even in times of budgetary constraints, given a proposed compact between the scientific ...
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“Science in Policy, Policy in Science”
Bulletin of the Atomic Scientists, 1964Statements on the federal investment in research and development, taken from the October 16, 1963 testimony of Dr. Wiesner (as Director of the Office of Science and Technology) before the House Subcommittee on Science, Research, and Development.
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Qualitative Health Research, 2007
Qualitative research struggles against a tide of quantitative methods. To assist in this struggle, it is useful to consider the historical and philosophical origins of quantitative methods as well as criticisms that have been raised against them. Although these criticisms have often been restricted to discussions in the philosophy of science, they ...
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Qualitative research struggles against a tide of quantitative methods. To assist in this struggle, it is useful to consider the historical and philosophical origins of quantitative methods as well as criticisms that have been raised against them. Although these criticisms have often been restricted to discussions in the philosophy of science, they ...
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Information Science Versus Science Policy
Science, 2000E mboldened by the proliferation of photocopiers and by success in getting “fair use” recognized by the 1976 Copyright Act, U.S. research universities have banked on the potential for technology to reduce library costs.
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Social Science, Policy Science
1991This chapter will emphasize, as characteristics that determine the character of, and the rules appropriate for the discourse of economics, its reference universe as a social science, and its role as a critical component of the political system as a policy science.
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