Results 41 to 50 of about 4,197,929 (308)

Science in non-hegemonic countries

open access: yesRevue d'anthropologie des connaissances, 2008
What does non-hegemonic country mean? This dossier was indeed intended to deal with knowledge in “developing” countries. However, it tries to avoid the conventional enumeration of stigmas (poverty, illiteracy, epidemics, low investment and infrastructure,
Philippe Losego, Rigas Arvanitis
doaj   +1 more source

Non-governmental organizations and multi-sited marine conservation science: A case study [PDF]

open access: yes, 2010
Non-governmental organizations (NGOs) are now major players in the realm of environmental conservation. While many environmental NGOs started as national organizations focused around single-species protection, governmental advocacy, and preservation of
Hastings, Jesse
core  

What do I make of your Latinorum? Sensitivity auditing of mathematical modelling

open access: yes, 2012
In their book Uncertainty and Quality of Science for Policy (1990), Funtowicz and Ravetz argued the need to extend traditional methods and techniques of quality assurance in policy-related science.
Funtowicz, Silvio   +3 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Grant Research Support in Russia: What Can We Learn from the Russian Science Foundation’s First Grant Competition?

open access: yesForesight and STI Governance, 2017
This paper studies the Russian Science Foundation’s first grant competition, which was held in 2014 to select exploratory or basic research projects, in order to shed light on the following two questions: (1) who wins the grants, and (2) what factors ...
Yuri Simachev   +2 more
doaj   +1 more source

The rhetoric of “science diplomacy": Innovation for the EU's scientific cooperation? EL-CSID Working Paper Issue 2018/16 • April 2018 [PDF]

open access: yes, 2018
In the recent years, the EU policy discourse has endorsed the notion of “science diplomacy” that points to the interaction between scientific research and foreign policy as instrumental in the societal and political progress.
Penca, Jerneja
core  

Why people attend science festivals : interests, motivations and self-reported benefits of public engagement with research [PDF]

open access: yes, 2014
As a form of public engagement, science festivals have rapidly expanded in size and number over recent years. However, as with other domains of informal public engagement that are not linked to policy outcomes, existing research does not fully address ...
Buckley N   +24 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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