Results 251 to 260 of about 5,361,695 (314)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Editorial: Spatial and regional mapping of brain neural communication. [PDF]

Front Cell Neurosci
Paluh JL, Das D, Mukherjee A.
europepmc   +1 more source

A comparison between dissociative subtypes of PTSD and CPTSD among trauma-exposed adolescents. [PDF]

Eur J Psychotraumatol
Bi Y, Cao C, Chen W, Liu Y, Liu P, Luo S, Zhang B, Qin H, Tang Y, Pan Y, Wang L.   +10 more
europepmc   +1 more source

Response to Letter: A 3-mm protrusion threshold after pediatric forearm ESIN: a rule-out safety margin, not a decision rule. [PDF]

Acta Orthop
Brattgjerd JE, Aasheim C, Rosenberg A, Fotland C, Halvorsen V.   +4 more
europepmc   +1 more source

Stable Isotope Composition of Skin Layers Confirms Trophic Differentiation of Baird's and Sato's Beaked Whales (Berardius spp.) in the Western North Pacific. [PDF]

Rapid Commun Mass Spectrom
Filatova OA, Fedutin ID, Bobyr IG, Titova OV, Ragimov MO, Hoyt E, Tsurikov SM, Tiunov AV.   +7 more
europepmc   +1 more source

Narratives of contingency as historical evidence for philosophical arguments of contingency: pathway decisions in the early development of molecular genetics. [PDF]

Hist Philos Life Sci
de Cock W.
europepmc   +1 more source

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The logical study of science

Synthese, 1982
The relation between logic and philosophy of science, often taken for granted, is in fact problematic. Although current fashionable criticisms of the usefulness of logic are usually mistaken, there are indeed difficulties which should be taken seriously — having to do, amongst other things, with different “scientific mentalities’ in the two disciplines
openaire   +4 more sources

Empirical studies to build a science of computer science

Communications of the ACM, 2007
We learn to develop software by building, testing, and evolving models.
Victor R. Basili, Marvin V. Zelkowitz
openaire   +1 more source