Results 121 to 130 of about 175,781 (305)

Cold War Operations: The Politics of Communist Confrontation, Part V - The Cuban Case History

open access: yes, 2018
A series of eight lectures by Professor Lyman B. Kirkpatrick of the Political Science Department, Brown University, given at the United States Naval War College during the 1966-67 term as a part of the Electives ...
Kirkpatrick, Lyman B.
core  

Episode 2: Understanding Regions through Oceans

open access: yes, 2023
Synopsis: In a series of essays for the Foreign Policy Research Institute, two scholars at the National Security Affairs Department at the U.S. Naval War College call for a reconceptualization of the global map in the way strategists think about ...
National Security Affairs Department, U.S. Naval War College
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Vietnam War and the laws of war: An examination of North Vietnam's military strategy and its compliance with the laws of war. [PDF]

open access: yes, 2011
The thesis focuses on the Vietnamese side of the Vietnam War. Though this war is one of the wars best documented, literature about the Vietnamese side is much less in comparison with that about the American side.
Le, Hai Van
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Just War and Human Rights

open access: yes, 2017
Warfare in the twenty-first century presents significant challenges to the modern state. Serious questions have arisen about the use of drones, target selection, civilian exposure to harm, intervening for humanitarian reasons, and war as a means of ...
Burkhardt, Todd
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Military demonstrations as digital spectacles: How virtual presentations of AI decision-support systems shape perceptions of war and security

open access: yesEuropean Journal of International Security
The growing reliance of militaries on artificial intelligence (AI) and machine learning (ML) technologies means that private software companies are assuming an increasingly central role in the conception and development of the tools of contemporary ...
Robin Vanderborght, Anna Nadibaidze
doaj   +1 more source

Science-based healthcare organization for Great Patriotic War veterans [PDF]

open access: yesСаратовский научно-медицинский журнал, 2015
The article summarizes the results of healthcare management of Great Patriotic War veterans for the last 20 years. This period included approbation and improvement of high-technology science-based and efficient healthcare system for war veterans ...
Lipatova Т.Е.   +4 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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