Results 161 to 170 of about 175,781 (305)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Suicides, suicide attempts and suicidal ideation among children and young people exposed to war: a scoping review. [PDF]
Silwal S +5 more
europepmc +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
War-Related Disruptions and Health Service Outcomes Among Internally Displaced Persons in Tigray, Ethiopia: Evidence From Adigrat City. [PDF]
Tekulu FB +3 more
europepmc +1 more source
International commodity prices, growth and the outbreak of Civil War in Sub-Saharan Africa [PDF]
To learn more about the effect of economic conditions on civil war, we examine whether Sub-Saharan civil wars are more likely to start following downturns in the international price of countries’ main export commodities.
Antonio Ciccone, Markus Brückner
core
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Science and the War on Truth and Coronavirus
Geoffrey P. Dobson
doaj +1 more source
Exposure to war-related trauma and symptoms of complex posttraumatic stress disorder among children and adolescents in Gaza. [PDF]
El-Khodary B +4 more
europepmc +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

