Results 91 to 100 of about 1,688,715 (313)

STATUTUL ŞTIINŢELOR EDUCAŢIEI (Sinteză)

open access: yesStudia Universitatis Moldaviae: Stiinte ale Educatiei, 2007
This study emphasizes the education sciences status and its analysis from a historical and epistemological perspective. It has mainly in sight the delimitation between the authentic education sciences (developed from the basis matrix of pe- dagogy) and
USM ADMIN
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Explanation and analysis of Islamization of science and its implications for education [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2007
In the past few centuries, globe has gone through many changes. The outstanding appearance of these developments is the industrial revolution of 17th century. The modernity as an idea has progressed in the same period of time.
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Challenges and Proposed Strategies for Enhancing the Comprehensive Program of Justice, Excellence, and Productivity in Medical Education: A case Study of Arak University of Medical Sciences [PDF]

open access: yesJournal of Medical Education and Development
Introduction: The Comprehensive Program of justice, excellence, and productivity in Medical Education, as the most recent reform initiative in Iran’s higher health education system, is currently being implemented in Iranian medical sciences universities.
Mohanna Rajabi, raheleh soltani
doaj  

Education for development in the context of various theoretical approaches within educational sciences

open access: yesNauki o Wychowaniu, 2018
The concept of education for development has been – next to other educational concepts – subject to many attempts of redefinition, which are often determined by different pragmatic and ideological postulates.
Adnan Tufekčić
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Barriers and facilitators of preoperative education within Enhanced Recovery after Surgery (ERAS) programs [PDF]

open access: yes, 2017
Providing sufficient and timely pre-operative education is essential for clients undergoing surgery within Enhanced Recovery after Surgery (ERAS) programs.
University of Lethbridge. Faculty of Health Sciences   +1 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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