Results 121 to 130 of about 1,688,715 (313)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Çağdaş Bir Din Eğitimi Teorisi Olarak Çoğulcu Din Eğitimi Modeli Batı Örneği
Dini Araştırmalar, 2015 One of the most striking features of our century is its pluralistic character This situation is valid for both the west and the east. Although the west has mostly a Christian population, it is a fact that millions of people who have different faiths and ...
Mustafa Köylü
doaj
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Guyana Education Sector Improvement Project: Indigenous Peoples Plan
, 2017 The objectives of the Guyana Education Sector Improvement Project are to support the Government in improving (i) the curricula and teaching quality at the pre-primary, primary, and lower secondary levels and (ii) learning environment in the Faculty of ...
Guyana. Ministry of Education
core
Theory of mind, emotional intelligence, and social stress in adolescents with HFASD [PDF]
, 2019 Many individuals with High-Functioning Autism Spectrum Disorder (HFASD) experience difficulties communicating effectively in their social world. It has been suggested that low levels of theory of mind, the ability to recognize that other individuals have
Rist, Paige +1 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interdisciplinary thinking in agricultural and life sciences higher education
, 2010 Interdisciplinary thinking as a skill appears to be of value to higher education students and those in employment. This idea is explored with reference to the agricultural and life sciences.
Tobi, H. +9 more
core
Road map of Iran’s internationalization of medical sciences education: Experience of Isfahan University of medical sciences [PDF]
مجله ایرانی آموزش در علوم پزشکی, 2017 Road map of Iran’s internationalization of medical sciences education: Experience of Isfahan University of medical ...
Habib Rezaei +4 more
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source