Results 201 to 210 of about 328,254 (286)

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Glimour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon s Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source

The total artificial heart: An existential transformation beyond technology. [PDF]

Eur J Heart Fail
Martin AC, Cholley B.
europepmc   +1 more source

Price: The Scientific Estate [PDF]

, 1966
Bullock, James F.
core   +1 more source

Structure‐Guided Engineering of a Cas12i Nuclease Unlocks Near‐PAMless Genome Editing

Advanced Science, EarlyView.
CRISPR‐Cas nucleases are limited by PAM requirements, restricting genome accessibility. Structure‐guided engineering of the compact Cas12i nuclease SF01 produced three variants with near‐PAMless, enabling efficient editing at diverse 5'‐NNTN‐3' sites. These nucleases expand the editable portion of the human genome more than fourfold, enabling efficient
Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian‐Kang Zhu   +15 more
wiley   +1 more source

Fundamental physics, existential risks and human futures. [PDF]

Philos Trans A Math Phys Eng Sci
Kent A.
europepmc   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

Advanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu, Zhongcheng Li, Qian Ren, Ziqian Lu, Yubing Zhang, Yili Guo, Ruomeng Li, Die Hu, Linglin Zhang   +8 more
wiley   +1 more source

The application of industry 4.0 into the company's production activities through effective decision-making. [PDF]

Sci Rep
Tashkinov AG.
europepmc   +1 more source

Dual Bipolar Resistive Switching in Wafer‐Scalable 2D Perovskite Oxide Nanosheets‐Based Memristor

Advanced Science, EarlyView.
A wafer‐scalable memristor based on 2D Sr2Nb3O₁₀ perovskite oxide nanosheets exhibits dual bipolar resistive switching through controllable oxygen ion migration and redox reactions. This single device enables both STDP and anti‐STDP synaptic functions, achieving 86.4% MNIST accuracy in supervised spiking neural networks, offering a compact, energy ...
Sohwi Kim, Chansoo Yoon, Haena Yim, Taeyoon Kim, Hoyoung Suh, Woohyeon Ryu, Gwangtaek Oh, Jihoon Jeon, Kwanyoung Oh, Yeonjoo Jeong, Ji‐Won Choi, Bae Ho Park   +11 more
wiley   +1 more source

The Beckman legacy and the future of interdisciplinary research. [PDF]

J R Soc Interface
Maren S.
europepmc   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source