Results 31 to 40 of about 20,274 (289)
Technology Portfolio and Role of Public Research Institutions in Industry 4.0: A Case of South Korea
The 4th industrial revolution has been a hot topic in various societies for several overlapping reasons. It may be a huge wave for researchers to navigate through. In this context, research institutions are not different from major industrial sectors, in
SungUk Lim, Junmo Kim
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The popular condemnation of «revolutionaryism» in post-Soviet Russia is seen as contradicting the global trends in scientific analysis of the role of revolutions in the development of society, according to which it is the revolutionary institutional ...
Yury V. Latov
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Scientific and Technological Revolution in the XX Century
The article analyzes the course and main results of the Scientific and technological revolution (NTR) of the middle and (partly) the second half of the 20th century – from the first tests of the atomic bomb to the introduction of personal computers and the Internet. The period of 1940 – 1980s.
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Theoretical approaches to the determination of the phenomenon of «technoglobalism»
This article examines the main factors and pre-conditions which caused the emergence of technoglobalism in the 20th century. The author identified the role of the research activity of transnational corporations in making this process more intensive, and ...
Olena Cherniavska
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Global Science and Technology Governance: Impetus, Challenges, and Prospects
Security risks arising from accelerating technological advances have become increasingly evident as humanity now stands on the threshold of a new industrial revolution.
Sun Haiyong
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Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley +1 more source

