Results 31 to 40 of about 18,149 (295)

Interpretations of scientific-technological revolution in Lithuania during Soviet period [PDF]

, 2021
Straipsnyje analizuojamos mokslo ir technikos revoliucijos (MTR) interpretacijos sovietmečio Lietuvos filosofijoje. Rekonstruojama šios problemos aiškinimo oficialioji ideologinė schema, glaustai apibūdinami esminiai jos aspektai: mokslo virtimo gamybine
Kabelka, Gintaras
core   +1 more source

Technology Portfolio and Role of Public Research Institutions in Industry 4.0: A Case of South Korea

Applied Sciences, 2019
The 4th industrial revolution has been a hot topic in various societies for several overlapping reasons. It may be a huge wave for researchers to navigate through. In this context, research institutions are not different from major industrial sectors, in
SungUk Lim, Junmo Kim
doaj   +1 more source

From В«RevolutionВ» to В«TransformationsВ» and В«ChangesВ»? Development of Discourses of Analysis Qualitative Social Change

Социологическая наука и социальная практика, 2021
The popular condemnation of «revolutionaryism» in post-Soviet Russia is seen as contradicting the global trends in scientific analysis of the role of revolutions in the development of society, according to which it is the revolutionary institutional ...
Yury V. Latov
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Scientific-technical revolution — important lessons of unimportant concept [PDF]

, 2020
This paper focuses on the concept of the scientific-technical revolution. This concept is relevant today most of all in the context of historiographic studies of the Soviet period or the reflection of contemporary technological transformation from the ...
Shipovalova, Lada V.
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Global Science and Technology Governance: Impetus, Challenges, and Prospects

China Quarterly of International Strategic Studies, 2021
Security risks arising from accelerating technological advances have become increasingly evident as humanity now stands on the threshold of a new industrial revolution.
Sun Haiyong
doaj   +1 more source

Can Quantum Biology lead to a scientific revolution? [PDF]

, 2019
Quantum mechanics has led to a scientific revolution in the 20th century. The accumulation of ad-hoc modifications has led to a paradigm shift resulting in great technological advances as well as deep phenomenological questions about the world we live in.
Jahangiri, Ali Reza
core   +1 more source