Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Correction: Epidemiological study of strongyle infections in equines in Egypt: prevalence and risk factors. [PDF]
Frontiers Production Office.
europepmc +1 more source
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Retraction Note: Machine learning-driven evaluation of mechanical and microstructural properties of agro-waste-derived geopolymer concrete. [PDF]
Elboughdiri N +5 more
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Correction: Gene driven analytical learning model for accurate breast cancer diagnosis. [PDF]
Hesham F, Abbassy MM, Abdalla M.
europepmc +1 more source
New visual culture of science: analysis of graphical abstracts in the life science journal "Cell". [PDF]
Ariga K.
europepmc +1 more source
How to build reproducibility into scientific publishing. [PDF]
Szabo C.
europepmc +1 more source
Early Career Reviewer Hub: Paving the way for the next generation of peer reviewers. [PDF]
Fuentes S, De la Rosa MA.
europepmc +1 more source

