Results 81 to 90 of about 79,301,386 (246)

Using an explicit query and a topic model for scientific article recommendation. [PDF]

open access: yesEduc Inf Technol (Dordr), 2023
Smail B, Aliane H, Abdeldjalil O.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Abu Ali ibn Sino’s scientific heritage related to pedagogy [PDF]

open access: yes
This article discusses the scientific heritage and views of the great scientist Abu Ali ibn Sina, who contributed to world civilization, on the upbringing of the future generation, the science of pedagogy, and his ...
Mubinaxon Xayrullo-qizi Xirmonboyeva   +1 more
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Mapping Spatial and Temporal Changes of Global Corporate Research and Development Activities by Conducting a Bibliometric Analysis

open access: yesQuaestiones Geographicae, 2017
Corporate research and development (R&D) activities have long been highly concentrated in a handful of world cities. This is due to the fact that these cities (e.g., Tokyo, New York, London, and Paris) are home to the largest and most powerful ...
Csomós György
doaj   +1 more source

Types de chaînes de référence dans les articles de recherche de format IMRAD

open access: yesDiscours, 2019
Many research articles in experimental sciences present a standardized form known as the IMRAD format, an acronym for “Introduction, Methods, Results and Discussion”. Each of these sections has a specific purpose (presenting the framework, describing the
Bruno Oberle
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Word Embedding for Rhetorical Sentence Categorization on Scientific Articles

open access: yesJournal of ICT Research and Applications, 2018
A common task in summarizing scientific articles is employing the rhetorical structure of sentences. Determining rhetorical sentences itself passes through the process of text categorization.
Ghoziyah Haitan Rachman   +2 more
doaj   +1 more source

How well do doctors understand a scientific article in English when it is not their first language? A randomised controlled trial. [PDF]

open access: yesBMJ Open, 2021
Rostadmo M   +7 more
europepmc   +1 more source

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