Results 121 to 130 of about 15,657,223 (266)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Average-based versus high-and low-impact indicators for the evaluation of scientific distributions [PDF]

open access: yes
Albarran et al. (2011a) introduced a novel methodology for the evaluation of citation distributions consisting of a pair of high- and a low-impact measures defined over the set of articles with citations below or above a critical citation level CCL ...
Javier Ruiz-Castillo   +2 more
core  

Linguistic Hedges in Scientific Articles on Humanities

open access: yesВестник Новосибирского государственного университета. Серия: история, филология
Purpose. By using a corpus of 120 Russian scientific articles on humanities the study analyzed linguistic actualizers of hedging as a metadiscourse strategy contributing to the efficient communication between an author and a reader.
O. A. Boginskaya
doaj   +1 more source

Describing and mapping scientific articles on alcohol globally for the period 2010-2021: a bibliometric analysis. [PDF]

open access: yesBMJ Open, 2022
Jaeger L   +6 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

[Scientific Articles]

open access: yes, 1962
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Weickhardt, Leonard W.
core  

Creating Logical Flow When Writing Scientific Articles. [PDF]

open access: yesJ Korean Med Sci, 2021
Barroga E, Matanguihan GJ.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy