Results 41 to 50 of about 15,657,223 (266)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Between fetishism and survival : is the scientific article an academic commodity? [PDF]
, 2007 This article discusses the possible meanings of the intense prevailing concern in academic circles over the notion of research productivity, as reflected in an excess number of articles published in various scientific journals.
Sanz-Valero, Javier, Castiel, Luis D.
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Barriers to Quality Nursing Burn Care in Moi Teaching and Referral Hospital in Kenya [PDF]
, 2022 Background The incidence of burns has significantly increased over the last decades. Although there is an extensive amount of literature on burns related injuries in Kenya, there is no evidence of studies which have examined barriers to quality nursing ...
Ballidawa, Joice +2 more
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Pearls for publishing papers: Tips and tricks
Indian Journal of Dermatology, 2016 With the stringent regulations from various academic bodies making it desirable for a post graduate resident to have submitted an original article prior to appearance for their exams or those working in teaching institutions to have published articles to
Karalikkattil T Ashique +1 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Introduction to Journal Impact Factor and h-index: Influence and relevance to contemporary scientific publishing and scholastic achievements [PDF]
, 2012 Scientific publishing is an essential component in the dissemination of research findings to both the academic community and general public. Among scholars in contemporary academic settings, the maxim publish or perish is well-known since publications ...
Yin, C-Y
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