Results 71 to 80 of about 15,657,223 (266)

MENINGKATKAN KUALITAS PENULISAN KARYA ILMIAH GURU-GURU SEKOLAH MENENGAH ATAS DI PARAKAN TEMANGGUNG

Rekayasa, 2016
Partners of this community service wereMadrasah Aliyah Negeri Parakan and SMK 17 Parakan Temanggung, Temanggung. This community serviceactivity was aimed atovercoming some of the problems faced by the teachers in both partners related to improving the ...
Rochmad Rochmad, Arief Agoestanto, Muhammad Kharis   +2 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Is Truth in Authority or Authority in Truth? Limitations to the Publication of Scientific Research [PDF]

, 2012
This paper examines the limitations and potential bias that exist within efforts to publish articles in exercise physiology. By discussing perceptions that: (a) greater truth appears to exist based on the publishing authority or journal title, (b) that ...
Steele, James, Fisher, James
core  

Study of the Academic Members Attitude about Main Factors of Not Approaching to Scientific Writing in Hamadan University of Medical Sciences

پزشکی بالینی ابن سینا, 2008
Background & Objective: one of the important indicators of scientific study and science production in the universities is original research and its scientific article.
Masoud Koorki, Hosein Mahjub, Nasrin Sheikh   +2 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

ChatGPT in Writing Scientific Articles: Friend or Foe? [PDF]

Journal of Medical Education and Development
Artificial intelligence tools such as GBT Chat have sparked many discussions among academics; While some see them as a useful tool to speed up research and others see it as a threat to the integrity of authorship.
Safiyehsadat Heydari
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Bisubstantive sentences in scientific discourse: Types of evaluation in scientific articles [PDF]

Известия Саратовского университета. Новая серия: Серия Филология, Журналистика
The article analyzes general and specific types of evaluation actualized in bisubstantive sentences in scientific articles in various specialties. It is noted that bisubstantive sentences are a productive means of expressing evaluative meaning.
Vatina, Anastasia Евгеньевна
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source