Describing and mapping scientific articles on alcohol globally for the period 2010-2021: a bibliometric analysis. [PDF]
Jaeger L +6 more
europepmc +1 more source
Institute for the Scientific Investigation of Sexuality Newsletter
Newsletter of the Institute for the Scientific Investigation containing organizational news as well as articles written by members or reprinted from other sources discussing AIDS and ...
Institute for the Scientific Investigation of Sexuality
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The quality of gender and sex integration in scientific articles resulting from health research funded by the Brazilian Ministry of Health 2004-2016. [PDF]
Batista RCP +2 more
europepmc +1 more source
Research on Scientific Journals: Implications for Editors and Authors [PDF]
A review of editorial policies of leading journals and of research relevant to scientific journals revealed conflicts between 'science' and 'scientists.” Owing to these conflicts, papers are often weak on objectivity and replicability.
JS Armstrong
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Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Creating Logical Flow When Writing Scientific Articles. [PDF]
Barroga E, Matanguihan GJ.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Research Status and Hotspots of Anticancer Natural Products Based on the Patent Literature and Scientific Articles. [PDF]
Shen J, Li J, Yu P, Du G.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source

